Successful Management of Chylothorax With Etilefrine: Case Report in 2 Pediatric Patients.

Autor: Muniz G; Division of General Academic Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Hidalgo-Campos J; Hospital de Emergencias Pediatricas, Lima, Perú; and., Valdivia-Tapia MDC; Hospital de Emergencias Pediatricas, Lima, Perú; and., Shaikh N; Division of General Academic Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Carreazo NY; Hospital de Emergencias Pediatricas, Lima, Perú; and yhuroc@gmail.com.; Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas, Lima, Perú.
Jazyk: angličtina
Zdroj: Pediatrics [Pediatrics] 2018 May; Vol. 141 (5).
DOI: 10.1542/peds.2016-3309
Abstrakt: Chylothorax is defined as the accumulation of chyle within the pleural space. Originally described in 1917 by Pisek, it is the most common cause of pleural effusion in the neonatal period. The leading cause of chylothorax is laceration of the thoracic duct during surgery, which occurs in 0.85% to 6.6% of children undergoing cardiothoracic surgery. Few authors of reports in the literature have looked at etilefrine, a relatively unknown sympathomimetic, as an option for the medical treatment of chylothorax. In this case report, we review the clinical course of 2 infants with type III esophageal atresia who developed chylothorax after thoracic surgery and were successfully treated with intravenous etilefrine after failing initial dietary and pharmacological management.
Competing Interests: POTENTIAL CONFLICT OF INTEREST: The authors have indicated they have no potential conflicts of interest to disclose.
(Copyright © 2018 by the American Academy of Pediatrics.)
Databáze: MEDLINE