Oral Mycosis Fungoides: A Report of Three Cases and Review of the Literature.

Autor: Rosebush MS; Louisiana State University, 1100 Florida Avenue, New Orleans, LA, 70119, USA. mroseb@lsuhsc.edu., Allen CM; Central Ohio Skin & Cancer, Inc., Westerville, OH, USA.; The Ohio State University, Columbus, OH, USA., Accurso BT; Oral Pathology Consultants, PLLC, Gross Pointe Woods, MI, USA., Baiocchi RA; Division of Hematology, The Ohio State University College of Medicine, Columbus, OH, USA., Cordell KG; Louisiana State University, 1100 Florida Avenue, New Orleans, LA, 70119, USA.
Jazyk: angličtina
Zdroj: Head and neck pathology [Head Neck Pathol] 2019 Sep; Vol. 13 (3), pp. 492-499. Date of Electronic Publication: 2018 Apr 26.
DOI: 10.1007/s12105-018-0923-5
Abstrakt: Mycosis fungoides (MF) and Sézary syndrome are clonal T-cell proliferations that exhibit skin homing and represent the majority of cutaneous T-cell lymphomas. Early MF is a diagnostic challenge as both the clinical and microscopic features often mimic benign inflammatory conditions. Oral MF is very rare and has been associated in the past with advanced disease and a poor prognosis. Skin lesions are present for an average of > 6 years before oral involvement occurs. The clinical appearance is highly variable with tongue, palate and gingiva most often affected. We report 3 additional cases of oral MF, including one in which oral lesions are the initial disease presentation. Survival in patients presenting with oral MF is improving and can be attributed to advances in therapy.
Databáze: MEDLINE
Externí odkaz: