Cognitive changes following multiple-modality exercise and mind-motor training in older adults with subjective cognitive complaints: The M4 study.

Autor: Boa Sorte Silva NC; School of Kinesiology, Faculty of Health Sciences, Western University, London, Ontario, Canada.; Lawson Health Research Institute, London, Ontario, Canada., Gill DP; Lawson Health Research Institute, London, Ontario, Canada.; Graduate Program in Health & Rehabilitation Sciences, Faculty of Health Sciences, Western University, London, Ontario, Canada.; School of Health Studies, Faculty of Health Sciences, Western University, London, Ontario, Canada.; Centre for Studies in Family Medicine, Department of Family Medicine, Western University, London, Ontario, Canada.; Canadian Centre for Activity and Aging, Western University, London, Ontario, Canada., Owen AM; The Brain and Mind Institute, Department of Psychology, Western University, London, Ontario, Canada., Liu-Ambrose T; Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada., Hachinski V; Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University, London, Ontario, Canada., Shigematsu R; Faculty of Education, Mie University, Tsu, Japan., Petrella RJ; School of Kinesiology, Faculty of Health Sciences, Western University, London, Ontario, Canada.; Lawson Health Research Institute, London, Ontario, Canada.; Graduate Program in Health & Rehabilitation Sciences, Faculty of Health Sciences, Western University, London, Ontario, Canada.; School of Health Studies, Faculty of Health Sciences, Western University, London, Ontario, Canada.; Centre for Studies in Family Medicine, Department of Family Medicine, Western University, London, Ontario, Canada.; Canadian Centre for Activity and Aging, Western University, London, Ontario, Canada.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2018 Apr 26; Vol. 13 (4), pp. e0196356. Date of Electronic Publication: 2018 Apr 26 (Print Publication: 2018).
DOI: 10.1371/journal.pone.0196356
Abstrakt: Background: We investigated the effects of multiple-modality exercise with additional mind-motor training on cognition in community-dwelling older adults with subjective cognitive complaints.
Methods: Participants (n = 127, mean age 67.5 [7.3] years, 71% women) were randomized to receive 45 minutes of multiple-modality exercise with additional 15 minutes of either mind-motor training (M4, n = 63) or control (balance, range of motion and breathing exercises [M2, n = 64]). In total, both groups exercised 60 minutes/day, 3 days/week, for 24 weeks. Standardized global cognitive functioning (GCF), concentration, reasoning, planning, and memory were assessed at 24 weeks and after a 28-week no-contact follow-up.
Results: There were no significant differences in the study primary outcomes. The M4 group, however, showed trends for greater improvements in GCF and memory (both, P = .07) compared to the M2 group at 24 weeks. Significant differences between group in GCF (P = .03) and memory (P = .02) were observed after the 28-week no-contact follow-up favouring the M4 group.
Discussion: Additional mind-motor training did not impart immediate greater benefits to cognition among the study participants.
Databáze: MEDLINE
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