Predicting Survival After Whole-brain Irradiation for Cerebral Metastases in Patients with Cancer of the Bladder.

Autor:	Rades D; Department of Radiation Oncology, University of Lübeck, Lübeck, Germany rades.dirk@gmx.net.; Faculty of Medicine, Hanoi Medical University, Hanoi, Vietnam., Dziggel L; Department of Radiation Oncology, University of Lübeck, Lübeck, Germany., Manig L; Department of Radiation Oncology, University of Lübeck, Lübeck, Germany., Janssen S; Department of Radiation Oncology, University of Lübeck, Lübeck, Germany.; Private Practice of Radiation Oncology, Hannover, Germany., Khoa MT; Faculty of Medicine, Hanoi Medical University, Hanoi, Vietnam.; Nuclear Medicine and Oncology Center, Bach Mai Hospital, Hanoi, Vietnam., Duong VN; Nuclear Medicine and Oncology Center, Bach Mai Hospital, Hanoi, Vietnam., Khiem VH; Nuclear Medicine and Oncology Center, Bach Mai Hospital, Hanoi, Vietnam., Schild SE; Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ, U.S.A.
Jazyk:	angličtina
Zdroj:	In vivo (Athens, Greece) [In Vivo] 2018 May-Jun; Vol. 32 (3), pp. 633-636.
DOI:	10.21873/invivo.11285
Abstrakt:	Background/aim: This study aimed to create a predictive tool for estimating the remaining lifespan of patients after whole-brain irradiation (WBI) for cerebral metastases from bladder cancer. Patients and Methods: In 34 of these patients clinical parameters were analyzed for survival including age at start of WBI, gender, Karnofsky score, number of cerebral metastases and involvement of extra-cranial sites of metastasis. Results: Involvement of extra-cranial sites (14%) and Karnofsky score (9%) showed the greatest difference regarding 6-month survival and were considered for the tool. Points were assigned based on the following: no involvement of extra-cranial sites=1 point, involvement of extra-cranial sites=0 points, Karnofsky score ≥70=1 point, Karnofsky score ≤60=0 points. Patients' scores were 0, 1 or 2 points with 6-month survival rates of 13%, 27% and 50%, respectively. Conclusion: Based on two clinical parameters, a tool was developed that may help estimate the lifespan of patients irradiated for cerebral metastases from bladder cancer. (Copyright© 2018, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu