Seroprevalences and Correlates of Hepatitis B and C Among Cameroonian Pregnant Women.

Autor: Fouelifack FY; Department of Obstetrics and Gynaecology, Higher Institute of Medical Technology of Nkolondom, Yaounde, Cameroon.; Obstetrics and Gynaecology Unit, Yaounde Central Hospital, Yaounde, Cameroon.; Research, Education and Health Development Group 'GARES-Falaise,' Dschang, Cameroon., Fouedjio JH; Obstetrics and Gynaecology Unit, Yaounde Central Hospital, Yaounde, Cameroon.; Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon., Fouogue JT; Department of Obstetrics and Gynaecology, Mbouda District Hospital, Mbouda, Cameroon.; Geneva University Hospitals, Geneva, Switzerland., Fouelifa LD; Faculty of Health Sciences, School of Armies Health Services of Lomé, University of Lomé, Lomé, Togo.
Jazyk: angličtina
Zdroj: Clinical medicine insights. Reproductive health [Clin Med Insights Reprod Health] 2018 Apr 16; Vol. 12, pp. 1179558118770671. Date of Electronic Publication: 2018 Apr 16 (Print Publication: 2018).
DOI: 10.1177/1179558118770671
Abstrakt: Background and Rationale: Viral hepatitis B (VHB) and viral hepatitis C (VHC) are major public health issues in resource-poor countries where vertical transmission remains high.
Aim: To assess prevalences and correlates of VHB and VHC among women attending antenatal clinic.
Methods: A cross-sectional study at the Yaounde Central Hospital from January 1 to June 30, 2016. We included 360 pregnant women who were screened for hepatitis B virus surface antigen (HbsAg) and VHCAb by rapid diagnostic test (DiaSpot Diagnostics, USA) followed by confirmation of positive results by a reference laboratory. Odds ratios (95% confidence interval [CI]) were used to measure associations between variables. Statistical significance was set for P -value <.05.
Results: Mean age was 27.9 ± 5.6 years. The prevalences of HbsAg and VHCAb were 9.4% (n = 34) and 1.7% (n = 6), respectively. Multiplicity of sex partners was significantly associated with HbsAg positivity (adjusted odds ratio [aOR]: 11.6; 95% CI: 5.1-26.7; P  < .001) while none of the studied factors was associated with VHCAb.
Conclusion: The high prevalence of hepatitis B among pregnant women supports systematic screening and free vaccination of pregnant women and women of childbearing age.
Competing Interests: Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze: MEDLINE
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