Transient global amnesia: Diffusion MRI findings.

Autor: Jain TP; Universal Medical Imaging, Canberra, Australia., Patel R; Stroke Service, Calvary Public Hospital, Bruce, Australia., Gawarikar Y; Stroke Service, Calvary Public Hospital, Bruce, Australia.; Australian National University, Canberra, ACT, Australia.
Jazyk: angličtina
Zdroj: The Indian journal of radiology & imaging [Indian J Radiol Imaging] 2018 Jan-Mar; Vol. 28 (1), pp. 6-9.
DOI: 10.4103/ijri.IJRI_12_17
Abstrakt: Introduction: Aim of this study is to identify and describe the MRI findings in patients with Transient Global Amnesia (TGA), specifically on Diffusion Weighted Imaging (DWI) sequence.
Methods: MRI findings in 12 patients with clinical diagnosis of TGA were retrospectively analysed. MRI brain was performed with a 3T scanner on 11 patients and 1.5T scanner on 1 patient. DWI were acquired at B value of 1000 s/mm 2 in 4 patients, 2000 s/mm 2 in 2 patients and both 1000 and 2000 s/mm 2 in 6 patients.
Results: There were 7 female and 5 male patients. The mean age was 65.67 years (range 61-74 years). The median time interval between the onset of symptom and MRI scan was 47.5 hours, range 25-114 hours. 11 of the 12 patients showed punctate foci of restricted diffusion in hippocampus (mean size 3.7 mm (range 2-6.5 mm). 10 patients showed foci in left hippocampus. Nine patients showed a single focus, 1 patient showed three foci and 1 patient showed four foci. In 6 patients who had DWI MRI at both B values, scans at B value of 1000 s/mm 2 revealed abnormality in 4 patients, while higher B value imaging improved sensitivity in one patient and one patient had a negative scan at both B values.
Conclusion: We have highlighted the MRI finding of typical punctate foci of bright signal in hippocampus seen on DWI in patients diagnosed with TGA. Detection on a routine stroke MRI protocol can avoid need for dedicated TGA protocols or repeat scan, improving the workflow.
Competing Interests: There are no conflicts of interest.
Databáze: MEDLINE
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