Prospective Observational Study on acute Appendicitis Worldwide (POSAW).

Autor: Sartelli M; Department of Surgery, Macerata Hospital, Macerata, Italy., Baiocchi GL; 2Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Di Saverio S; 3Emergency Surgery, Maggiore Hospital, Bologna, Italy., Ferrara F; 4General Surgery and Polytrauma, San Carlo Borromeo Hospital, Milan, Italy., Labricciosa FM; Department of Biomedical Sciences and Public Health, Unit of Hygiene, Preventive Medicine and Public Health, UNIVPM, Ancona, Italy., Ansaloni L; 6Department of Surgery, Bufalini Hospital, Cesena, Italy., Coccolini F; 6Department of Surgery, Bufalini Hospital, Cesena, Italy., Vijayan D; 7General Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Abbas A; 8Emergency Surgery, Mansoura University Hospital, Mansoura, Egypt., Abongwa HK; 9Emergency Surgery Unit, Maggiore University Hospital, Parma, Italy., Agboola J; Surgery, Kwara State General Hospital, Ilorin, Kwara Nigeria., Ahmed A; 11Surgery, Ahmadu Bello University Teaching Hospital Zaria, Zaria, Nigeria., Akhmeteli L; Surgery, First University Clinic, Tbilisi, Georgia., Akkapulu N; 13General Surgery, Baskent Universitesi Adana Eğitim ve Uygulama Hastanesi, Adana, Turkey., Akkucuk S; 14General Surgery, Training and Research Hospital of Mustafa Kemal University, Hatay, Turkey., Altintoprak F; 15General Surgery, Sakarya University School of Medicine, Sakarya, Turkey., Andreiev AL; 7General Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Anyfantakis D; Primary Care, Primary Health Care Centre of Kissamos, Chania, Greece., Atanasov B; 17Department of General Surgery, Medical University of Plovdiv, UMHAT Eurohospital, Plovdiv, Bulgaria., Bala M; 18General Surgery, Hadassah Medical Center, Jerusalem, Israel., Balalis D; Surgical Department, Agios Savvas Anticaner Hospital, Athens, Greece., Baraket O; General Surgery, Hospital Habib Bouguefa de Bizerte, Bizerte, Tunisia., Bellanova G; General Surgery, S.S. Annunziata Hospital, Taranto, Italy., Beltran M; Surgery, Hospital San Juan de Dios de La Serena, La Serena, Chile., Melo RB; 23General Surgery, Centro Hospitalar São João, Porto, Portugal., Bini R; 24General and Emergency Surgery, San Giovanni Bosco Hospital, Turin, Italy., Bouliaris K; Surgical Department, General Hospital of Larissa, Larissa, Greece., Brunelli D; Chirurgia, Città di Castello Hospital, Città di Castello, Italy., Castillo A; 27Department of Surgery, Harbor-UCLA Medical Center, Torrance, USA., Catani M; 28DEA, La Sapienza Università di Roma, Policlinico Umberto I, Rome, Italy., Che Jusoh A; General Surgery, Kuala Krai Hospital, Kuala Krai, Kelantan Malaysia., Chichom-Mefire A; Surgery and Obstetrics/Gynaecology, Regional Hospital, Limbe, Cameroon., Cocorullo G; 31Emergency Surgery, Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone, Palermo, Italy., Coimbra R; 32Trauma/Acute Care Surgery, University of California San Diego, San Diego, USA., Colak E; General Surgery, Samsun Training and Research Hospital, Samsun, Turkey., Costa S; 34Surgery, CHVNG/E, EPE, Vila Nova de Gaia, Portugal., Das K; 35General Surgery, Numune Training and Research Hospital, Adana, Turkey., Delibegovic S; 36Colorectal Surgery, Clinic for Surgery, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina., Demetrashvili Z; Surgery, Kipshidze Central University Hospital, Tbilisi, Georgia., Di Carlo I; 38Surgery, Hamad General Hospital, Doha, Qatar., Kiseleva N; 39General and Emergency Surgery, Riga East University Hospital 'Gailezers', Riga, Latvia., El Zalabany T; General Surgery, Bahrain Defence Force Hospital, Manama, Bahrain., Faro M; 41Department of General Surgery, Trauma and Emergency Surgery Division, ABC Medical School, Santo Andreì, SP Brazil., Ferreira M; 42General Surgery, Hospital Garcia de Orta, Lisbon, Portugal., Fraga GP; 43Division of Trauma Surgery, Hospital de Clinicas, University of Campinas (Unicamp), Campinas, Brazil., Gachabayov M; Department of Abdominal Surgery, Vladimir City Clinical Hospital of Emergency Medicine, Vladimir, Russia., Ghnnam WM; 45General Surgery Department, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt., Giménez Maurel T; 46Cirugía General y del Aparato Digestivo, Hospital Universitario Miguel Servet, Zaragoza, Spain., Gkiokas G; 47Second Department of Surgery, Aretaieion University Hospital, National and Kapodistrian University of Athens, Athens, Greece., Gomes CA; Surgery, Therezinha de Jesus University Hospital, Juiz de Fora, Brazil., Griffiths E; 49Upper GI/General Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Guner A; 50Department of General Surgery, Karadeniz Technical University, Farabi Hospital, Trabzon, Turkey., Gupta S; 51Surgery, Government Medical College and Hospital, Chandigarh, India., Hecker A; 52Department of General and Thoracic Surgery, University Hospital, Giessen, Germany., Hirano ES; 43Division of Trauma Surgery, Hospital de Clinicas, University of Campinas (Unicamp), Campinas, Brazil., Hodonou A; Chirurgie, Chud-Borgou/Alibori, Parakou, Benin., Hutan M; Surgical Department, Landesklinikum Hainburg, Hainburg An Der Donau, Austria., Ioannidis O; 554th Surgical Department, Aristotle University of Thessaloniki, Thessaloniki, Greece.; 56General Hospital 'George Papanikoalou', Thessaloniki, Greece., Isik A; 57General Surgery, Erzincan University Mengucek Gazi Training and Research Hospital, Erzincan, Turkey., Ivakhov G; General Surgery, City Hospital #1, Moscow, Russia., Jain S; 59Surgery, S M S Medical college, Jaipur, India., Jokubauskas M; 60Department of Surgery, Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Kaunas, Lithuania., Karamarkovic A; 61Clinic for Emergency Surgery, Faculty of Medicine University of Belgrade, Belgrade, Serbia., Kauhanen S; 62Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland., Kaushik R; 51Surgery, Government Medical College and Hospital, Chandigarh, India., Kavalakat A; 63General Surgery, Jubilee Mission Medical College & Research Institute, Thrissur, India., Kenig J; 643rd Department of General Surgery, Jagiellonian University Medical College, Krakow, Poland., Khokha V; Emergency surgery, City Hospital, Mozyr, Belarus., Khor D; 66Acute Care Surgery, LAC+USC Medical Center, California, USA., Kim D; 27Department of Surgery, Harbor-UCLA Medical Center, Torrance, USA., Kim JI; 67Department of Surgery, Inje University Ilsan Paik Hospital, Goyang, Republic of Korea., Kong V; 68Department of Surgery, Edendale Hospital, Pietermaritzburg, South Africa., Lasithiotakis K; General Surgery, Scarborough, York Teaching Hospital, Scarborough, UK., Leão P; General Surgery, Colorectal Unit, Hospital de Braga, Braga, Portugal., Leon M; 71General and Digestive Surgery, Hospital Fundación Jimenez Diaz, Madrid, Spain., Litvin A; Surgical Disciplines, Regional Clinical Hospital, Kaliningrad, Russia., Lohsiriwat V; 73Faculty of Medicine, Department of Surgery, Siriraj Hospital, Mahidol University, Bangkok, Thailand., López-Tomassetti Fernandez E; Department of Gastrointestinal Surgery, Insular University Hospital of Gran Canaria, Las Palmas, Spain., Lostoridis E; 1st Department of Surgery, Kavala General Hospital, Kavala, Greece., Maciel J; 27Department of Surgery, Harbor-UCLA Medical Center, Torrance, USA., Major P; 762nd Department of Surgery, Jagiellonian University Medical College, Krakow, Poland., Dimova A; 77Clinic of surgery, Department of Gastrointestinal Surgery, University Hospital Centre Zagreb, Zagreb, Croatia., Manatakis D; 78Surgical Department, Konstantopouleio General Hospital, Athens, Greece., Marinis A; 79First Department of Surgery, Tzaneio, Piraeus, Greece., Martinez-Perez A; 80Department of General and Digestive Surgery, Hospital Universitario Doctor Peset, Valencia, Spain., Marwah S; 81Department of General Surgery, Post-Graduate Institute of Medical Sciences, Rohtak, India., McFarlane M; 82Department of Surgery, Radiology, Anaesthetics and Intensive Care, University of the West Indies, Kingston, Jamaica.; 83University Hospital of the West Indies, Kingston, Jamaica., Mesina C; Department of Surgery Second Surgical Clinic, Emergency Hospital of Craiova, Craiova, Romania., Pędziwiatr M; 85Department of General Surgery and Emergency Medicine, University Hospital, Kraków, Poland., Michalopoulos N; 863rd Department of Surgery, Ahepa University Hospital, Thessaloniki, Greece., Misiakos E; 873rd Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Mohamedahmed A; General Surgery, Khartoum Teaching Hospital, Khartoum, Sudan., Moldovanu R; Department of Visceral, Digestive and Oncologic Surgery, Clinique Sainte Marie, Cambrai, France., Montori G; 6Department of Surgery, Bufalini Hospital, Cesena, Italy., Mysore Narayana R; General Surgery, K R Hospital, Mysore, India., Negoi I; General Surgery, Emergency Hospital of Bucharest, Bucharest, Romania., Nikolopoulos I; 92General Surgery, Lewisham and Greenwich NHS Trust, London, UK., Novelli G; 93General, Emergency Surgery, Infermi Hospital, Rimini, Italy., Novikovs V; 39General and Emergency Surgery, Riga East University Hospital 'Gailezers', Riga, Latvia., Olaoye I; 94Surgery, University of Ilorin Teaching Hospital, Ilorin, Nigeria., Omari A; 95General Surgery, King Abdullah University Hospital, Irbid, Jordan., Ordoñez CA; 96Division of Trauma and Acute Care Surgery, Department of Surgery, Fundación Valle del Lili and Universidad del Valle, Cali, Colombia., Ouadii M; Surgery Departement, Medical School of Fezm, Sidi Mohamed Benabdellah University, Fez, Morocco., Ozkan Z; General Surgery, Elazig Training and Research Hospital, Elazig, Turkey., Pal A; 99General Surgery, King George's Medical University, Lucknow, India., Palini GM; 93General, Emergency Surgery, Infermi Hospital, Rimini, Italy., Partecke LI; Surgery, University Hospital, Greifswald, Germany., Pata F; Department of General Surgery, Sant'Antonio Abate Hospital, Gallarate, Italy., Pędziwiatr M; 102Department of Emergency Surgery and Trauma Centre, University Hospital, Kraków, Poland., Pereira Júnior GA; 103Surgery and Anatomy, Clinics Hospital, Ribeirão Preto, Brazil., Pintar T; 104Abdominal surgery, UMC Ljubljana, Ljubljana, Slovenia., Pisarska M; 105Department of Endoscopic, Metabolic and Soft Tissue Tumors Surgery, The University Hospital in Krakow, Kraków, Poland., Ploneda-Valencia CF; 106General Surgery, Hospital Civil de Guadalajara 'Dr. Juan I. Menchaca', Guadalajara, Mexico., Pouggouras K; 1st Department of Surgery, Kavala General Hospital, Kavala, Greece., Prabhu V; 107Surgery, Bharati Vidyapeeth Deemed University Medical College & Hospital, Sangli, Maharashtra India., Ramakrishnapillai P; Laparoscopic and Metabolic Surgery, KIMS Hospital, Cochin, India., Regimbeau JM; 109Digestive Surgery, CHU Amiens-Picardie, Amiens, France., Reitz M; General Surgery, Hospital Municipal Dr. Jose de Carvalho Florence, Sao Jose Dos Campos, Brazil., Rios-Cruz D; General Surgery, Hospital General Regional # 1 I.M.S.S, Cuernavaca, Mexico., Saar S; Acute Care Surgery, North Estonia Medical Center, Tallinn, Estonia., Sakakushev B; General Surgery, University Hospital St George, Plovdiv, Bulgaria., Seretis C; 114General Surgery, Russells Hall Hospital, Birmingham, UK., Sazhin A; General Surgery, City Hospital #1, Moscow, Russia., Shelat V; 115General Surgery, Tan Tock Seng Hospital, Singapore, Singapore., Skrovina M; Surgery, Hospital & Oncological Centre Novy Jicin, Novy Jicin, Czech Republic., Smirnov D; General Surgery, Clinical Hospital at Chelyabinsk Station OJSC 'Russian Railways', Chelyabinsk, Russian Federation., Spyropoulos C; 1183rd Department of Surgery, IASO General Hospital, Athens, Greece., Strzałka M; 119General Surgery and Polytrauma, University Hospital, Medical College, Jagiellonian University, Kraków, Poland., Talving P; Acute Care Surgery, North Estonia Medical Center, Tallinn, Estonia., Teixeira Gonsaga RA; Cirurgia do Trauma, Hospital Escola Padre Albino, Catanduva, Brazil., Theobald G; 7General Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Tomadze G; 121Surgery Department #2, Tbilisi State Medical University, Tbilisi, Georgia., Torba M; General Surgery, Trauma University Hospital, Tirana, Albania., Tranà C; Department of Surgery, Macerata Hospital, Macerata, Italy., Ulrych J; 1231st Department of Surgery-Department of Abdominal Thoracic Surgery and Traumatology, General University Hospital, Prague, Czech Republic., Uzunoğlu MY; 14General Surgery, Training and Research Hospital of Mustafa Kemal University, Hatay, Turkey., Vasilescu A; First Surgical Clinic, St. Spiridon University Hospital, Iasi, Romania., Occhionorelli S; Emergency Surgery, S. Anna Teaching Hospital, Ferrara, Italy., Venara A; 126Digestive and Endocrinal Surgery, University Hospital, Angers, France., Vereczkei A; 127Department of Surgery, Medical School University of Pécs, Pécs, Hungary., Vettoretto N; Surgery, ASTS Spedali Civili Brescia, Montichiari, Italy., Vlad N; First Surgical Clinic, St. Spiridon University Hospital, Iasi, Romania., Walędziak M; 129Department of General, Oncological, Metabolic and Thoracic Surgery, Military Institute of Medicine in Warsaw, Warsaw, Poland., Yilmaz TU; 130Department of General Surgery, Kocaeli University, Kocaeli, Turkey., Yuan KC; Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan., Yunfeng C; 132Department of Surgery, Tianjin Nankai Hospital, Tianjin, China., Zilinskas J; 60Department of Surgery, Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Kaunas, Lithuania., Grelpois G; 109Digestive Surgery, CHU Amiens-Picardie, Amiens, France., Catena F; 8Emergency Surgery, Mansoura University Hospital, Mansoura, Egypt.
Jazyk: angličtina
Zdroj: World journal of emergency surgery : WJES [World J Emerg Surg] 2018 Apr 16; Vol. 13, pp. 19. Date of Electronic Publication: 2018 Apr 16 (Print Publication: 2018).
DOI: 10.1186/s13017-018-0179-0
Abstrakt: Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments.
Methods: This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016-September 30, 2016). All consecutive patients admitted to surgical departments with a clinical diagnosis of AA were included in the study.
Results: A total of 4282 patients were enrolled in the POSAW study, 1928 (45%) women and 2354 (55%) men, with a median age of 29 years. Nine hundred and seven (21.2%) patients underwent an abdominal CT scan, 1856 (43.3%) patients an US, and 285 (6.7%) patients both CT scan and US. A total of 4097 (95.7%) patients underwent surgery; 1809 (42.2%) underwent open appendectomy and 2215 (51.7%) had laparoscopic appendectomy. One hundred eighty-five (4.3%) patients were managed conservatively. Major complications occurred in 199 patients (4.6%). The overall mortality rate was 0.28%.
Conclusions: The results of the present study confirm the clinical value of imaging techniques and prognostic scores. Appendectomy remains the most effective treatment of acute appendicitis. Mortality rate is low.
Competing Interests: The data was completely anonymized, and no patient or hospital information was collected in the database. The study protocol was approved by the board of the WSES, and the study was conducted under its supervision. The board of the WSES grants the proper ethical conduct of the study.The authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Databáze: MEDLINE
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