| Autor: |
Claudio SR; Departments of Pathology., Handan BA; Biosciences., Gomes de Moura CF; Biosciences., Viana MB; Biosciences., Yamauchi LY; Human Movement Sciences, Federal University of São Paulo, UNIFESP, Santos, Brazil., Aguiar O Jr; Biosciences., Oshima CTF; Departments of Pathology., Ribeiro DA; Departments of Pathology. |
| Jazyk: |
angličtina |
| Zdroj: |
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) [Eur J Cancer Prev] 2019 Mar; Vol. 28 (2), pp. 109-114. |
| DOI: |
10.1097/CEJ.0000000000000424 |
| Abstrakt: |
Since its discovery as an antimicrobial agent, fluoride has been used in the control of dental caries. Many studies have shown that the chronic exposure of fluoride in high concentrations causes adverse effects in multiple organs; the use of bioactive compounds present in foods as a tool to mitigate the effects of fluoride could potentially be useful for populations in different parts of the world are exposed to fluoride in a chronic and systemic way. Thus, the aim of this comprehensive review is to present and discuss the published papers that focused on the use of polyphenols and nonpolyphenols that can mitigate the harmful activities promoted by fluoride exposure. Certainly, these data will contribute toward a better understanding of the role of food compounds in the pathological outcomes induced by fluoride. The new information will be added to that already available for regulatory purposes as a safe way to promote oral healthcare and prevent oral carcinogenesis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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