Efficacy of Aedes aegypti control by indoor Ultra Low Volume (ULV) insecticide spraying in Iquitos, Peru.

Autor: Gunning CE; Department of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC United States of America., Okamoto KW; Department of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC United States of America., Astete H; Naval Medical Research Unit No. 6, 3230 Lima Pl., Washington DC, Lima and Iquitos, Peru., Vasquez GM; Naval Medical Research Unit No. 6, 3230 Lima Pl., Washington DC, Lima and Iquitos, Peru., Erhardt E; Department of Mathematics and Statistics, University of New Mexico, Albuquerque, NM, United States of America., Del Aguila C; Department of Environmental Sanitation, Peruvian Ministry of Health, Iquitos, Peru., Pinedo R; Department of Environmental Sanitation, Peruvian Ministry of Health, Iquitos, Peru., Cardenas R; Department of Environmental Sanitation, Peruvian Ministry of Health, Iquitos, Peru., Pacheco C; Department of Environmental Sanitation, Peruvian Ministry of Health, Iquitos, Peru., Chalco E; Department of Environmental Sanitation, Peruvian Ministry of Health, Iquitos, Peru., Rodriguez-Ferruci H; Loreto Regional Health Directorate, Iquitos, Peru., Scott TW; Department of Entomology and Nematology, University of California, Davis, CA, United States of America., Lloyd AL; Biomathematics Graduate Program and Department of Mathematics, North Carolina State University, Raleigh, NC, United States of America., Gould F; Department of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC United States of America., Morrison AC; Naval Medical Research Unit No. 6, 3230 Lima Pl., Washington DC, Lima and Iquitos, Peru.; Department of Entomology and Nematology, University of California, Davis, CA, United States of America.
Jazyk: angličtina
Zdroj: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2018 Apr 06; Vol. 12 (4), pp. e0006378. Date of Electronic Publication: 2018 Apr 06 (Print Publication: 2018).
DOI: 10.1371/journal.pntd.0006378
Abstrakt: Background: Aedes aegypti is a primary vector of dengue, chikungunya, Zika, and urban yellow fever viruses. Indoor, ultra low volume (ULV) space spraying with pyrethroid insecticides is the main approach used for Ae. aegypti emergency control in many countries. Given the widespread use of this method, the lack of large-scale experiments or detailed evaluations of municipal spray programs is problematic.
Methodology/principal Findings: Two experimental evaluations of non-residual, indoor ULV pyrethroid spraying were conducted in Iquitos, Peru. In each, a central sprayed sector was surrounded by an unsprayed buffer sector. In 2013, spray and buffer sectors included 398 and 765 houses, respectively. Spraying reduced the mean number of adults captured per house by ~83 percent relative to the pre-spray baseline survey. In the 2014 experiment, sprayed and buffer sectors included 1,117 and 1,049 houses, respectively. Here, the sprayed sector's number of adults per house was reduced ~64 percent relative to baseline. Parity surveys in the sprayed sector during the 2014 spray period indicated an increase in the proportion of very young females. We also evaluated impacts of a 2014 citywide spray program by the local Ministry of Health, which reduced adult populations by ~60 percent. In all cases, adult densities returned to near-baseline levels within one month.
Conclusions/significance: Our results demonstrate that densities of adult Ae. aegypti can be reduced by experimental and municipal spraying programs. The finding that adult densities return to approximately pre-spray densities in less than a month is similar to results from previous, smaller scale experiments. Our results demonstrate that ULV spraying is best viewed as having a short-term entomological effect. The epidemiological impact of ULV spraying will need evaluation in future trials that measure capacity of insecticide spraying to reduce human infection or disease.
Databáze: MEDLINE
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