Fluoroalkylsulfonyl Chlorides Promoted Vicinal Chloro-fluoroalkylthiolation of Alkenes and Alkynes.

Autor:	Jiang L; School of Chemical Engineering , Nanjing University of Science and Technology , Nanjing 210094 , P. R. China., Ding T; School of Chemical Engineering , Nanjing University of Science and Technology , Nanjing 210094 , P. R. China., Yi WB; School of Chemical Engineering , Nanjing University of Science and Technology , Nanjing 210094 , P. R. China., Zeng X; School of Chemical Engineering , Nanjing University of Science and Technology , Nanjing 210094 , P. R. China., Zhang W; Centre for Green Chemistry and Department of Chemistry , University of Massachusetts Boston , 100 Morrissey Boulevard , Boston , Massachusetts 02125 , United States.
Jazyk:	angličtina
Zdroj:	Organic letters [Org Lett] 2018 Apr 20; Vol. 20 (8), pp. 2236-2240. Date of Electronic Publication: 2018 Apr 06.
DOI:	10.1021/acs.orglett.8b00581
Abstrakt:	The unprecedented use of CF 3 SO 2 Cl for direct bifunctional chloro-trifluoromethylthiolation of alkenes and alkynes is reported. CF 3 SCl, which is generated by the reduction of PPh 3 , undergoes electrophilic addition and then chlorination to give the bifunctionalized products without using an additional chlorine source. The method is also applicable for chloro-difluoromethylthiolation using CF 2 HSO 2 Cl.
Databáze:	MEDLINE
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