What are the prevalence, characteristics and significance of fetal lateral neck cysts detected in an early anatomical scan?

Autor: Sukenik Halevy R; Department of OB-GYN, Meir Medical Center, Kfar Saba, Israel. Riki.sukenik@gmail.com.; Genetics Institute, Meir Medical Center, 59 Tchernichovsky St., Kfar Saba, Israel. Riki.sukenik@gmail.com.; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Riki.sukenik@gmail.com., Mashiach Friedler J; Ultrasound Unit, Meir Medical Center, Kfar Saba, Israel., Hershko-Klement A; Department of OB-GYN, Meir Medical Center, Kfar Saba, Israel.; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Biron-Shental T; Department of OB-GYN, Meir Medical Center, Kfar Saba, Israel.; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Markovitch O; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.; Ultrasound Unit, Meir Medical Center, Kfar Saba, Israel., Tepper R; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.; Ultrasound Unit, Meir Medical Center, Kfar Saba, Israel.
Jazyk: angličtina
Zdroj: Archives of gynecology and obstetrics [Arch Gynecol Obstet] 2018 Jul; Vol. 298 (1), pp. 51-58. Date of Electronic Publication: 2018 Apr 03.
DOI: 10.1007/s00404-018-4747-z
Abstrakt: Purpose: This study evaluated the association of fetal lateral neck cysts (FLNC) with adverse pregnancy outcomes, in relation to specific sonographic characteristics and co-existing findings.
Methods: Pregnancies in which FLNC were detected by a single examiner in early anatomical scans (14-16 weeks) were included. Data regarding the pregnancy and its outcome were retrieved from telephone-based questionnaires, patient charts and from the examiner's reports.
Results: 654 cases of FLNC were detected among 9446 early anatomical scans (6.9%). Complete data regarding 219 pregnancies were available. FLNC were significantly more prevalent in males (65.2%). The prevalence of heart malformations was 3.2% [all were non-isolated cases or with abnormal nuchal translucency (NT) and/or nuchal fold (NF)]. Amniocentesis performed in 165 pregnancies was abnormal in 1.2%. Among 206 children born from this cohort, adverse medical outcomes were reported in 5.3%. The likelihood of adverse pregnancy outcomes was significantly higher in non-isolated cases and in cases with abnormal NT or NF. Sonographic characteristics such as cyst size and bilateral findings were not linked to adverse pregnancy outcomes.
Conclusion: Isolated FLNC are benign findings which do not require additional work up. FLNC with additional sonographic abnormalities are associated with a significantly increased risk for adverse pregnancy outcomes.
Databáze: MEDLINE
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