Orthotopic Liver Transplantation: Preliminary Analysis of Complications With Grafts From Elderly Donors.

Autor: Naranjo-Izurieta JR; Management Unit of Critical Care, University Hospital Virgen del Rocío, Seville, Spain. Electronic address: jose.naranjo.10@gmail.com., Ruiz de Azúa-López Z; Management Unit of Critical Care, University Hospital Virgen del Rocío, Seville, Spain; Intrahospital Transplant Coordination, University Hospital Virgen del Rocío, Seville, Spain., Lameirao J; Management Unit of Critical Care, University Hospital Virgen del Rocío, Seville, Spain., Martín-Villén L; Management Unit of Critical Care, University Hospital Virgen del Rocío, Seville, Spain; Intrahospital Transplant Coordination, University Hospital Virgen del Rocío, Seville, Spain., Roldán-Reina A; Management Unit of Critical Care, University Hospital Virgen del Rocío, Seville, Spain., Porras-López M; Management Unit of Critical Care, University Hospital Virgen del Rocío, Seville, Spain., Rodríguez-Rodríguez A; Management Unit of Critical Care, University Hospital Virgen del Rocío, Seville, Spain., Egea-Guerrero JJ; Management Unit of Critical Care, University Hospital Virgen del Rocío, Seville, Spain; Sectorial Coordination of Transplants, Sevilla-Huelva, Sevilla, Spain.
Jazyk: angličtina
Zdroj: Transplantation proceedings [Transplant Proc] 2018 Mar; Vol. 50 (2), pp. 644-645.
DOI: 10.1016/j.transproceed.2017.12.034
Abstrakt: Objective: This study aims to determine if donor grafts of patients older than 65 years develop more post-transplantation complications than those of younger patients.
Design: This is a retrospective, observational study of liver transplant recipients during 12 months in Virgen del Rocio University Hospital. We compare incidence rates of reperfusion syndrome, acute kidney injury, and need for intra- and postoperative red blood cell transfusions in two donor age groups in which group A is <65 years old and group B is ≥65 years old.
Results: Sixty cases were included. Reperfusion syndrome, acute kidney injury, and both intra- and postoperative red blood cell transfusion were more frequent in group A than group B (11.4% vs. 4%, P = .390; 44% vs. 32%, P = .423; 68.8% vs. 48%, P = .120; and 70.6% vs. 64%, P = .779, respectively). Six recipients (17.1%) died at 12 months from group A whereas there were no deaths register in group B during that time (P = .036).
Conclusion: Our results showed that including elderly donors does not aggravate incidence of complications, emphasizing that advanced age should not be an exclusion criteria for liver transplantation.
(Copyright © 2017 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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