Botulism in pregnancy - a clinical approach to diagnosis and management.

Autor: Rimawi BH; a University of South Alabama , Division of Maternal-Fetal Medicine , Mobile , AL , USA.
Jazyk: angličtina
Zdroj: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians [J Matern Fetal Neonatal Med] 2019 Sep; Vol. 32 (18), pp. 3125-3132. Date of Electronic Publication: 2018 Apr 06.
DOI: 10.1080/14767058.2018.1457641
Abstrakt: Botulism is a life-threatening toxin mediated disease that often presents with a sudden rapid onset of paralysis of their skeletal muscles with subsequent respiratory compromise and sudden death. Given the natural physiological changes during pregnancy, pregnant women with botulism may experience a more exaggerated course and have worse outcomes compared to nonpregnant women. Medical providers caring for such patients should not only maintain a high level of suspicion for botulism, but administration of an antitoxin early in their care can help reduce morbidity and mortality, while awaiting confirmatory laboratory results. It is not uncommon for a medical provider caring for these women to mistakenly associate the signs and symptoms associated with botulism with pregnancy-related findings; therefore, this article illustrates a clinical algorithmic approach to caring for these women, including a systematic approach to establishing a diagnosis and management plan for pregnant women with botulism.
Databáze: MEDLINE