The risk of hypertension and cardiovascular disease in women with uterine fibroids.

Autor:	Haan YC; Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands., Diemer FS; Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands.; Department of Cardiology, Academic Hospital Paramaribo, Paramaribo, Suriname., Van Der Woude L; Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands., Van Montfrans GA; Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands.; Department of Internal Medicine, Academic Medical Center, Amsterdam, the Netherlands., Oehlers GP; Department of Cardiology, Academic Hospital Paramaribo, Paramaribo, Suriname., Brewster LM; Department of Internal Medicine, Academic Medical Center, Amsterdam, the Netherlands.; Department of Public Health, Anton de Kom University of Suriname, Paramaribo, Suriname.
Jazyk:	angličtina
Zdroj:	Journal of clinical hypertension (Greenwich, Conn.) [J Clin Hypertens (Greenwich)] 2018 Apr; Vol. 20 (4), pp. 718-726. Date of Electronic Publication: 2018 Mar 22.
DOI:	10.1111/jch.13253
Abstrakt:	Women with fibroids have a notably high hypertension risk. However, adjusted data regarding other cardiovascular disease (CVD) risk factors are scarce. In this cross-sectional study, CVD risk factors, hemodynamic parameters, and asymptomatic organ damage were analyzed between women with uterine fibroids and controls in a multi-ethnic population. In total, 104 women with self-reported fibroids and 624 controls were included. Women with fibroids had significantly higher odds to have hypertension (OR 3.4; 95% CI 2.2-5.2), diabetes (1.7; 1.0-2.9), and hypercholesterolemia (1.8; 1.1-3.2). After adjustment for confounders, only the odds ratio for hypertension was significant (1.8; 1.1-3.1). Asymptomatic organ damage occurred significantly more often in women with fibroids (66.7%; 95% CI 55.8%-77.6% vs 42.9%; 38.0-47.8 in controls), especially in the younger age group (respectively 48.5%; 31.1%-65.9% vs 22.1%; 17.0-27.2). In this study, women with fibroids had a remarkably high hypertension risk compared to controls, with more asymptomatic organ damage, in particular young women. (©2018 Wiley Periodicals, Inc.)
Databáze:	MEDLINE
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