| Autor: |
Post EH; Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium., Vincent JL; Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium. jlvincent@intensive.org. |
| Jazyk: |
angličtina |
| Zdroj: |
Critical care (London, England) [Crit Care] 2018 Mar 22; Vol. 22 (1), pp. 81. Date of Electronic Publication: 2018 Mar 22. |
| DOI: |
10.1186/s13054-018-1962-8 |
| Abstrakt: |
The importance of personalized blood pressure management is well recognized. Because renal pressure-flow relationships may vary among patients, understanding how renal autoregulation may influence blood pressure control is essential. However, much remains uncertain regarding the determinants of renal autoregulation in circulatory shock, including the influence of comorbidities and the effects of vasopressor treatment. We review published studies on renal autoregulation relevant to the management of acutely ill patients with shock. We delineate the main signaling pathways of renal autoregulation, discuss how it can be assessed, and describe the renal autoregulatory alterations associated with chronic disease and with shock. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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