Neuropsychological outcomes after pulmonary endarterectomy using moderate hypothermia and periodic circulatory arrest.

Autor:	Vanini B; Unit of Cardiac Surgery, Intrathoracic Transplantation and Pulmonary Hypertension, University of Pavia School of Medicine, Foundation IRCCS Policlinico San Matteo, Pavia, Italy; Department of Brain and Behavioral Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy. Electronic address: benedetta.vanini@virgilio.it., Grazioli V; Unit of Cardiac Surgery, Intrathoracic Transplantation and Pulmonary Hypertension, University of Pavia School of Medicine, Foundation IRCCS Policlinico San Matteo, Pavia, Italy., Sciortino A; Unit of Cardiac Surgery, Intrathoracic Transplantation and Pulmonary Hypertension, University of Pavia School of Medicine, Foundation IRCCS Policlinico San Matteo, Pavia, Italy., Pin M; Unit of Cardiac Surgery, Intrathoracic Transplantation and Pulmonary Hypertension, University of Pavia School of Medicine, Foundation IRCCS Policlinico San Matteo, Pavia, Italy., Merli VN; Unit of Cardiac Surgery, Intrathoracic Transplantation and Pulmonary Hypertension, University of Pavia School of Medicine, Foundation IRCCS Policlinico San Matteo, Pavia, Italy., Celentano A; Unit of Cardiac Surgery, Intrathoracic Transplantation and Pulmonary Hypertension, University of Pavia School of Medicine, Foundation IRCCS Policlinico San Matteo, Pavia, Italy., Parisi I; Unit of Cardiac Surgery, Intrathoracic Transplantation and Pulmonary Hypertension, University of Pavia School of Medicine, Foundation IRCCS Policlinico San Matteo, Pavia, Italy., Klersy C; Service of Biometrics and Statistics, Foundation IRCCS Policlinico San Matteo, Pavia, Italy., Petrucci L; Rehabilitation Unit, Foundation IRCCS Policlinico San Matteo, Pavia, Italy., Salati M; Unit of Cardiac Surgery, Intrathoracic Transplantation and Pulmonary Hypertension, University of Pavia School of Medicine, Foundation IRCCS Policlinico San Matteo, Pavia, Italy., Politi P; Department of Brain and Behavioral Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy., D'Armini AM; Unit of Cardiac Surgery, Intrathoracic Transplantation and Pulmonary Hypertension, University of Pavia School of Medicine, Foundation IRCCS Policlinico San Matteo, Pavia, Italy.
Jazyk:	angličtina
Zdroj:	The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation [J Heart Lung Transplant] 2018 Jul; Vol. 37 (7), pp. 860-864. Date of Electronic Publication: 2018 Feb 19.
DOI:	10.1016/j.healun.2018.02.007
Abstrakt:	Background: In this prospective, single-center, observational study, we investigated the association between repeated short periods of circulatory arrest with moderate hypothermia during pulmonary endarterectomy (PEA) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) and different neuropsychological dimensions. Methods: We examined 70 patients with CTEPH, >18 to 80 years of age, who had been treated with PEA. Neuropsychological testing was performed. Results: Learning ability and delayed memory remained well within the normal range for patients' age. We found a statistically significant post-surgical improvement in motor speed, which was accompanied by a better quality of life and reduced symptoms of depression and anxiety. Conclusion: PEA with repeated short periods of circulatory arrest in CTEPH did not result in any neuropsychological complications and may even lead to post-surgical psychological improvements. (Copyright © 2018 International Society for the Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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