Cerebellar Proliferative Angiopathy Associated with a Pontine Telangiectasia and a Developmental Venous Anomaly.

Autor: Vilela MD; Neurological Surgery, Mater Dei Hospital, Belo Horizonte, Brazil; Department of Neurological Surgery, University of Washington, Seattle, Washington, USA. Electronic address: vilelamd@gmail.com., Tazinaffo U; Neuroradiology, Mater Dei Hospital, Belo Horizonte, Brazil.
Jazyk: angličtina
Zdroj: World neurosurgery [World Neurosurg] 2018 Jun; Vol. 114, pp. 106-110. Date of Electronic Publication: 2018 Mar 13.
DOI: 10.1016/j.wneu.2018.03.029
Abstrakt: Various mixed associations between arteriovenous malformations, cavernous malformations, developmental venous anomalies, and capillary telangiectasias have been described, and a common pathophysiologic event has been suggested to be present, although it is yet to be elucidated. We depict herein the imaging features of a patient who presented with a spontaneous cerebellar hemorrhage, in whom radiologic studies demonstrated a pontine telangiectasia, a brainstem/cerebellar developmental venous anomaly, and a cerebellar proliferative angiopathy. This unique, not previously reported combination of lesions shows that the spectrum of mixed vascular malformations continues to expand. A pathophysiologic mechanism related to the angiogenesis seen in these malformations is also hypothesized.
(Copyright © 2018 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE