Basolateral amygdala circuitry in positive and negative valence.

Autor: O'Neill PK; Department of Neuroscience, Columbia University, 1051 Riverside Drive Unit 87, New York, NY 10032, USA., Gore F; Department of Bioengineering, Stanford University, 443 Via Ortega, Stanford, CA 94305, USA., Salzman CD; Department of Neuroscience, Columbia University, 1051 Riverside Drive Unit 87, New York, NY 10032, USA; Department of Psychiatry, Columbia University, 1051 Riverside Drive Unit 87, New York, NY 10032, USA; New York State Psychiatric Institute, 1051 Riverside Drive Unit 87, New York, NY 10032, USA; Kavli Institute for Brain Sciences, 1051 Riverside Drive Unit 87, New York, NY 10032, USA. Electronic address: cds2005@columbia.edu.
Jazyk: angličtina
Zdroj: Current opinion in neurobiology [Curr Opin Neurobiol] 2018 Apr; Vol. 49, pp. 175-183. Date of Electronic Publication: 2018 Mar 08.
DOI: 10.1016/j.conb.2018.02.012
Abstrakt: All organisms must solve the same fundamental problem: they must acquire rewards and avoid danger in order to survive. A key challenge for the nervous system is therefore to connect motivationally salient sensory stimuli to neural circuits that engage appropriate valence-specific behavioral responses. Anatomical, behavioral, and electrophysiological data have long suggested that the amygdala plays a central role in this process. Here we review experimental efforts leveraging recent technological advances to provide previously unattainable insights into the functional, anatomical, and genetic identity of neural populations within the amygdala that connect sensory stimuli to valence-specific behavioral responses.
(Copyright © 2018 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: