[Levomepromazine as adjuvant sedation in a pediatric intensive care unit].

Autor:	Becerra V; Unidad de Cuidados Intensivos Pediátricos, Hospital de Pediatría 'Juan P. Garrahan', Buenos Aires, Argentina. draverobecerra@yahoo.com.ar., Buamscha D, Ponce C, Cambaceres C, Noman A, Galván ME, Lenz M
Jazyk:	Spanish; Castilian
Zdroj:	Vertex (Buenos Aires, Argentina) [Vertex] 2017 Nov; Vol. 28 (136), pp. 411-415.
Abstrakt:	Introduction: Sedation of patients in pediatric ICU extubated and in weaning of mechanic ventilation is diffcult under regular sedation, because of the tolerance and/or abstinence generated by its sustained use. The objective of this study is to describe the use of Levomepromazine as sedative coadjuvant in these patients. Population and Methods: Observational and longitudinal study in intensive care from Juan P. Garrahan Pediatric Hospital. Patients older than 2 years were included, extubated and in weaning of mechanic ventilation with requirements of additional sedation. The level of basal sedation and post-intervention (levomepromazine 0.5 mg/kg every 8 hours) were evaluated with Ramsay and Khalil scales. Doses of regular sedatives were compared before and after the indication. It was considered positive an increase of 1 in the scales, or a decrease of 20% in the regular sedatives doses. Results: 36 patients, medium age of 8,5 years, average doses of levomepromazine 0.38 mg/kg. 97% showed positive result. The regular sedative doses were reduced more than 20% after the intervention. No adverse effects or deceased were registered.
Databáze:	MEDLINE
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