C1-C2 arthrodesis after spontaneous Propionibacterium acnes spondylodiscitis: Case report and literature analysis.

Autor: di Russo P; Department of Neurosurgery, University of Pisa, AOUP, Pisa, Italy., Tascini C; Department of Infectious Diseases, Cotugno Hospital, Naples, Italy., Benini ME; Department of Neurosurgery, University of Pisa, AOUP, Pisa, Italy., Martini C; GSpine4, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy., Lepori P; GSpine4, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Jazyk: angličtina
Zdroj: Surgical neurology international [Surg Neurol Int] 2018 Jan 22; Vol. 9, pp. 14. Date of Electronic Publication: 2018 Jan 22 (Print Publication: 2018).
DOI: 10.4103/sni.sni_96_17
Abstrakt: Background: Propionibacterium acnes ( P. acnes ) is a microaerophilic anaerobic Gram-positive rod responsible for acne vulgaris. Although it is often considered to be a skin contaminant, it may act as a virulent agent in implant-associated infections. Conversely, spontaneous infectious processes have been rarely described.
Case Description: Here, we describe a 43-year-old female with C1-C2 spondylodiscitis attributed to P. acnes infection. Despite long-term antibiotic treatment, computed tomography demonstrated erosion of the C1 and C2 vertebral complex that later warranted a fusion. One year postoperatively, the patient was asymptomatic.
Conclusions: Clinical knowledge of P. acnes virulence in spontaneous cervical spondylodiscitis allows early diagnosis, which is necessary to prevent or reduce complications such as cervical deformity with myelopathy or mediastinitis.
Competing Interests: There are no conflicts of interest.
Databáze: MEDLINE