| Autor: |
Falk RH, Plehn JF, Deering T, Schick EC Jr, Boinay P, Rubinow A, Skinner M, Cohen AS |
| Jazyk: |
angličtina |
| Zdroj: |
The American journal of cardiology [Am J Cardiol] 1987 Feb 15; Vol. 59 (5), pp. 418-22. |
| DOI: |
10.1016/0002-9149(87)90948-9 |
| Abstrakt: |
Thirty-one patients with documented cardiac amyloidosis were compared to 39 control subjects with left ventricular hypertrophy to determine specific 2-dimensional echocardiographic features of amyloid. In 16 patients, increased myocardial echogenicity was present when a single short-axis view was examined, and had a sensitivity of 63% and a specificity of 74% for the diagnosis of amyloidosis. When complete echocardiograms were reviewed (15 patients), an improved sensitivity of 87% and specificity of 81% based on increased echogenicity was seen. Increased atrial septal thickness was present in 60% of amyloid patients and no controls. The combination of increased myocardial echogenicity and increased atrial thickness was 60% sensitive and 100% specific for the diagnosis of amyloidosis. The ratio of electrocardiographic voltage (S in V1 + R in V5 or V6) to left ventricular cross-sectional area also was examined. A ratio of less than 1.5 was 82% sensitive and 83% specific for amyloid (excluding the 2 patients with left bundle branch block), but added little to the diagnosis as determined from the 2-dimensional echocardiogram. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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