Autor: |
Farina N; Michigan Medicine Department of Pharmacy, Ann Arbor., Miller JT |
Jazyk: |
angličtina |
Zdroj: |
Critical care nursing quarterly [Crit Care Nurs Q] 2018 Apr/Jun; Vol. 41 (2), pp. 121-128. |
DOI: |
10.1097/CNQ.0000000000000193 |
Abstrakt: |
Direct oral anticoagulants are becoming increasingly popular in outpatient use. These medications have lacked specific reversal agents. However, this is changing. The Federal Food and Drug Administration approved idarucizumab for reversal of dabigatran in 2016, and another agent, andexanet alfa, is currently in clinical trials for reversal of rivaroxaban and apixaban. This article examines the efficacy and safety of these emerging reversal agents, as well as other historical agents for reversal of direct oral anticoagulants. |
Databáze: |
MEDLINE |
Externí odkaz: |
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