Role of Magnesium in Vitamin D Activation and Function.

Autor: Uwitonze AM, Razzaque MS
Jazyk: angličtina
Zdroj: The Journal of the American Osteopathic Association [J Am Osteopath Assoc] 2018 Mar 01; Vol. 118 (3), pp. 181-189.
DOI: 10.7556/jaoa.2018.037
Abstrakt: Nutrients usually act in a coordinated manner in the body. Intestinal absorption and subsequent metabolism of a particular nutrient, to a certain extent, is dependent on the availability of other nutrients. Magnesium and vitamin D are 2 essential nutrients that are necessary for the physiologic functions of various organs. Magnesium assists in the activation of vitamin D, which helps regulate calcium and phosphate homeostasis to influence the growth and maintenance of bones. All of the enzymes that metabolize vitamin D seem to require magnesium, which acts as a cofactor in the enzymatic reactions in the liver and kidneys. Deficiency in either of these nutrients is reported to be associated with various disorders, such as skeletal deformities, cardiovascular diseases, and metabolic syndrome. It is therefore essential to ensure that the recommended amount of magnesium is consumed to obtain the optimal benefits of vitamin D.
Databáze: MEDLINE