The Nordic Prudent Diet Reduces Risk of Cognitive Decline in the Swedish Older Adults: A Population-Based Cohort Study.

Autor:	Shakersain B; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, 113 30 Stockholm, Sweden. behnaz.shakersain@ki.se., Rizzuto D; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, 113 30 Stockholm, Sweden. Debora.Rizzuto@ki.se., Larsson SC; Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden. behnaz.shakersain@ki.se., Faxén-Irving G; Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 141 57 Huddinge, Sweden. Debora.Rizzuto@ki.se., Fratiglioni L; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, 113 30 Stockholm, Sweden. laura.fratiglioni@ki.se.; Stockholm Gerontology Research Center, 113 30 Stockholm, Sweden. laura.fratiglioni@ki.se., Xu WL; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, 113 30 Stockholm, Sweden. weili.xu@ki.se.; Department Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Qixiangtai Road 22, Heping District, Tianjin 300070, China. weili.xu@ki.se.
Jazyk:	angličtina
Zdroj:	Nutrients [Nutrients] 2018 Feb 17; Vol. 10 (2). Date of Electronic Publication: 2018 Feb 17.
DOI:	10.3390/nu10020229
Abstrakt:	Appropriate dietary pattern for preserving cognitive function in northern Europe remains unknown. We aimed to identify a Nordic dietary pattern index associated with slower cognitive decline compared to the Mediterranean-DASH Intervention for Neurodegenerative Delay, Mediterranean Diet, Dietary Approaches to Stop Hypertension, and Baltic Sea Diet indices. A total of 2223 dementia-free adults aged ≥60 were followed for 6 years. Mini-Mental State Examination was administrated at baseline and follow-ups. Dietary intake was assessed by 98-item food frequency questionnaire, and the Nordic Prudent Dietary Pattern (NPDP) was identified. Data were analysed using mixed-effects and parametric survival models and receiver operating characteristic curves with adjustment for potential confounders. Moderate (β = 0.139, 95% CI 0.077-0.201) and high adherence (β = 0.238, 95% CI 0.175-0.300) to NPDP were associated with less cognitive decline compared to other four indices. High adherence to NPDP was also associated with the lowest risk of MMSE decline to ≤24 (HR = 0.176, 95% CI 0.080-0.386) and had the greatest ability to predict such decline (area under the curve = 0.70). Moderate-to-high adherence to the NPDP may predict a better-preserved cognitive function among older adults in Nordic countries. Regional dietary habits should be considered in developing dietary guidelines for the prevention of cognitive impairment and dementia. Competing Interests: The authors declare no conflict of interest.
Databáze:	MEDLINE
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