[The efficacy of cocarnit in diabetic neuropathy].

Autor:	Kotov SV; Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Isakova EV; Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Leidvoll VY; Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Belova YA; Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Volchenkova TV; Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Borodin AV; Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Shvedov VA; Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia.
Jazyk:	ruština
Zdroj:	Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2018; Vol. 118 (1), pp. 37-42.
DOI:	10.17116/jnevro20181181137-42
Abstrakt:	Aim: To study the efficacy of the complex therapy, including cocarnit (group B vitamins, triphosadenine and nicotinamide), of diabetic neuropathy. Material and Methods: Forty-one patients with diabetes mellitus type 2 and distal symmetric sensorimotor polyneuropathy were examined. Patients were divided into 2 groups. Patients of the main group (n=26) received complex therapy, including cocarnit, and patients of the comparison group (n=15) received standard treatment. Results and Conclusion: The positive dynamics based on the VAS (р=0.0001), TSS (р=0.0001), NSS (р=0.001), NDS (р=0.0431), SF-36 (р=0.0008), electroneuromyographic results and glycated hemoglobin levels was observed in the main group. In patients of the comparison group, the positive dynamics was instable; the scores of clinical scales did not reach statistical significance. The results suggest the use of cocarnit in the complex treatment of patients with diabetic neuropathy.
Databáze:	MEDLINE
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