| Autor: |
Vaidya SR; ICMR-National Institute of Virology,20-A Dr Ambedkar Road,Pune 411001,India., Tilavat SM; Directorate of Medical and Health Services, State Health Society,IDSP Shri VBCH Campus,Silvassa 396230,India., Kumbhar NS; ICMR-National Institute of Virology,20-A Dr Ambedkar Road,Pune 411001,India., Kamble MB; ICMR-National Institute of Virology,20-A Dr Ambedkar Road,Pune 411001,India. |
| Jazyk: |
angličtina |
| Zdroj: |
Epidemiology and infection [Epidemiol Infect] 2018 Mar; Vol. 146 (4), pp. 476-480. Date of Electronic Publication: 2018 Feb 13. |
| DOI: |
10.1017/S0950268818000201 |
| Abstrakt: |
During 9th December 2016 and 12th February 2017, 149-chickenpox cases were reported in a tribal and industrial zone of Rakholi (n = 80) and Surangi (n = 69) villages from Union Territory of India. An epidemiological investigation was performed to assess the characteristics and determinants of the chickenpox outbreak. Overall, the attack rate per 100 population in Rakholi village (n = 1757) was 4.5% and 19.1% in Surangi village (n = 360). Ages of the cases were ranged from 6 months to 55 years and there were 53 females and 96 males. For the laboratory investigations, 25 serum samples, three urine specimens, three throat swabs and six blister/skin swabs were collected from 37-suspected chickenpox cases. Altogether, 30-suspected cases were laboratory confirmed by either IgM EIA or varicella zoster virus (VZV) DNA PCR. Both VZV-specific IgM and IgG antibodies were detected in 19-suspected cases. Two suspected cases showed the presence of VZV-specific IgG antibodies but not IgM antibodies. On the contrary, three suspected cases showed VZV-specific IgM but not IgG antibodies. Overall, 31 of 37-suspected cases (including one equivocal case) were laboratory confirmed. The partial sequencing of ORF-28 gene of VZV revealed circulation of clade-1 viruses. In conclusion, this investigation provides detail information about the chickenpox outbreak in the tribal and industrial setting from India. Furthermore, the study emphasises the need to investigate more chickenpox outbreaks in different parts of India. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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