Differences in neuropsychiatric symptoms between nursing home residents with young-onset dementia and late-onset dementia.

Autor:	Appelhof B; a Department of Primary and Community Care , Center for Family Medicine, Geriatric Care and Public Health , Radboud University Nijmegen , Medical Centre , Nijmegen , the Netherlands.; b Archipel, Landrijt , Knowledge Center For Specialized Care , Eindhoven , the Netherlands.; c Radboud Alzheimer Center , Nijmegen , The Netherlands., Bakker C; a Department of Primary and Community Care , Center for Family Medicine, Geriatric Care and Public Health , Radboud University Nijmegen , Medical Centre , Nijmegen , the Netherlands.; c Radboud Alzheimer Center , Nijmegen , The Netherlands.; d Florence, Mariahoeve , Center for Specialized Care in Young-Onset Dementia , The Hague , the Netherlands., Van Duinen-van Den IJssel JCL; a Department of Primary and Community Care , Center for Family Medicine, Geriatric Care and Public Health , Radboud University Nijmegen , Medical Centre , Nijmegen , the Netherlands.; c Radboud Alzheimer Center , Nijmegen , The Netherlands., Zwijsen SA; e Department of General Practice and Elderly Care Medicine/EMGO + Institute for Health and Care Research , VU Medical Centre , Amsterdam , the Netherlands., Smalbrugge M; e Department of General Practice and Elderly Care Medicine/EMGO + Institute for Health and Care Research , VU Medical Centre , Amsterdam , the Netherlands., Verhey FRJ; f School For Mental Health and Neuroscience , Alzheimer Center Limburg , Maastricht University Medical Center , Maastricht , the Netherlands., de Vugt ME; f School For Mental Health and Neuroscience , Alzheimer Center Limburg , Maastricht University Medical Center , Maastricht , the Netherlands., Zuidema SU; g Department of General Practice , University of Groningen , University Medical Center Groningen , Groningen , the Netherlands., Koopmans RTCM; a Department of Primary and Community Care , Center for Family Medicine, Geriatric Care and Public Health , Radboud University Nijmegen , Medical Centre , Nijmegen , the Netherlands.; c Radboud Alzheimer Center , Nijmegen , The Netherlands.; h De Waalboog 'Joachim en Anna' , Center for Specialized Geriatric Care , Nijmegen , the Netherlands.
Jazyk:	angličtina
Zdroj:	Aging & mental health [Aging Ment Health] 2019 May; Vol. 23 (5), pp. 581-586. Date of Electronic Publication: 2018 Feb 09.
DOI:	10.1080/13607863.2018.1428935
Abstrakt:	Objective: The aims of the current study are (1) to explore the differences in neuropsychiatric symptoms (NPS) between young-onset dementia (YOD) and late-onset dementia (LOD), and (2) to investigate whether the possible differences can be attributed to differences in dementia subtype, gender, psychotropic drug use (PDU), or dementia severity. Method: Three hundred and eighty-six nursing home (NH) residents with YOD and 350 with LOD were included. Multilevel modeling was used to compare NPS between the groups . Furthermore, dementia subtype, gender, PDU, and dementia severity were added to the crude multilevel models to investigate whether the possible differences in NPS could be attributed to these characteristics. Results: Higher levels of apathy were found in NH residents with YOD. After the characteristics were added to the models, also lower levels of verbally agitated behaviors were found in YOD . Conclusion: We recommend that special attention be paid to interventions targeting apathy in YOD. Although no differences in other NPS were found, the PDU rates were higher in YOD, suggesting that the threshold for the use of PDU in the management of NPS is lower. This underscores the need for appropriate attention to non-pharmacological interventions for the management of NPS in YOD.
Databáze:	MEDLINE
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