To use the brief psychiatric rating scale to detect disorganized speech in schizophrenia: Findings from the REAP-AP study.

Autor:	Chon Park Y; Department of Neuropsychiatry, Hanyang University Guri Hospital, Guri, Republic of Korea., Kanba S; Department of Neuropsychiatry, Graduate School of Medicine, Kyushu University, Fukuoka, Japan., Chong MY; Chang Gung Memorial Hospital, Chang Gung University School of Medicine, Chiayi, Taiwan., Tripathi A; Department of Psychiatry, King George's Medical University, Chowk, Lucknow, India., Kallivayalil RA; Pushpagiri Institute of Medical Sciences, Tiruvalla, Kerala, India., Avasthi A; Department of Psychiatry, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India., Grover S; Department of Psychiatry, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India., Chee KY; Tunku Abdul Rahman Institute of Neuroscience, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia., J Tanra A; Wahidin Sudirohusodo University, Makassar, Sulawesi Selatan, Indonesia., Maramis MM; Department of Psychiatry, Dr. Soetomo Hospital, Faculty of Medicine, Airlangga University, Surabaya, Indonesia., Yang SY; Department of Pharmacy, Songde Branch, Tapei City Hospital, Tapei, Taiwan., Sartorius N; Association of the Improvement of Mental Health Programs, Geneva, Switzerland., Tan CH; Department of Pharmacology, National University Hospital, Singapore, Singapore., Shinfuku N; Department of Social Welfare, School of Human Sciences, Seinan Gakuin University, Fukuoka, Japan., Park SC; Department of Psychiatry, Inje University College of Medicine and Haeundae Paik Hospital, Busan, Republic of Korea. Electronic address: cogito-ergo-sum@hanmail.net.
Jazyk:	angličtina
Zdroj:	The Kaohsiung journal of medical sciences [Kaohsiung J Med Sci] 2018 Feb; Vol. 34 (2), pp. 113-119. Date of Electronic Publication: 2017 Oct 20.
DOI:	10.1016/j.kjms.2017.09.009
Abstrakt:	Our study aimed to assess the psychometric validity of the conceptual disorganization item and other items of the Brief Psychiatric Rating Scale (BPRS) for detecting disorganized speech in patients with schizophrenia. We included 357 schizophrenia patients with disorganized speech and 1082 without disorganized speech from the survey centers in India, Indonesia, Japan, Malaysia, and Taiwan, using the data from the Research on Asian Psychotropic Patterns for Antipsychotics (REAP-AP) study. After adjusting the effects of confounding variables, a binary logistic regression model was fitted to identify BPRS items independently associated with disorganized speech. Receiver operating characteristic (ROC) curves were used to identify optimum cut-off scores and their sensitivities and specificities for detecting disorganized speech. After adjusting the effects of confounding variables, the fitted binary logistic regression model indicated that conceptual disorganization (P < 0.0001), uncooperativeness (P = 0.010) and excitement (P = 0.001) were independently associated with disorganized speech. The ROC curve revealed that the conceptual disorganization item could accurately detect disorganized speech in patients with schizophrenia both separately and in combination with uncooperativeness and excitement. The subscale for conceptual disorganization, uncooperativeness and excitement items in the BPRS is a promising psychometric tool for detecting disorganized speech. (Copyright © 2017. Published by Elsevier Taiwan.)
Databáze:	MEDLINE
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