| Autor: |
Unterrainer M, Maihoefer C, Cyran CC, Bartenstein P, Niyazi M, Albert NL |
| Jazyk: |
angličtina |
| Zdroj: |
Clinical nuclear medicine [Clin Nucl Med] 2018 Apr; Vol. 43 (4), pp. 287-288. |
| DOI: |
10.1097/RLU.0000000000001985 |
| Abstrakt: |
In this case of suspected sphenoid wing meningioma, Ga-DOTATATE PET/CT showed a somatostatin receptor (SSR)-expressing tumor with extension to the nasopharynx and SSR-expressing cervical lymph nodes. Subsequent biopsy from the nasopharynx revealed an Epstein-Barr virus (EBV)-associated, undifferentiated World Health Organization type 3 nasopharyngeal carcinoma (NPC), a potential clinical pitfall due to the reported high SSR expression of this tumor subtype. In consideration of the high target-to-background contrast, SSR ligands might be superior to F-FDG for EBV-associated NPC PET imaging, particularly at the skull base. Somatostatin receptor ligands might furthermore offer interesting theranostic possibilities for patients with advanced/extensive EBV-associated NPC. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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