| Autor: |
Tetsumoto S; Dept. of Respiratory Medicine, Nishinomiya Municipal Central Hospital., Okada K, Nagata H, Toyota S, Tanaka S, Niki T, Tsuruta N, Higaki N, Niju T, Oka Y, Nezu R, Ikeda T |
| Jazyk: |
japonština |
| Zdroj: |
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2017 Nov; Vol. 44 (12), pp. 1452-1454. |
| Abstrakt: |
The patient was a 54-year-old woman with anaplastic lymphoma kinase-positive stage III B lung cancer. She received 4 courses of carboplatin(CBDCA)plus paclitaxel(PTX)plus bevacizumab(Bev)chemotherapy and crizotinib. Chemotherapy reduced the size of the primary site and mediastinal lymphadenopathy; however, the right supraclavicular and subcarinal lymph nodes were enlarged again during crizotinib treatment. Because it was an oligo-recurrence, we performed radiotherapy for these lymph nodes and changed systemic chemotherapy to alectinib. After 16 months, the patient exhibited esophageal stenosis due to subcarinal lymphadenopathy. We performed a subtotal esophagectomy, which improved the quality of life, and she was continued on an oral treatment of alectinib. Therefore, we suggest that an invasive surgical treatment is useful for oligo-recurrence cases. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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