[The spectrum of genetic alterations in anaplastic gliomas: and anaplastic oligodendrogliomas].

Autor: Ryzhova MV; Burdenko Neurosurgical Institute, Moscow, Russia, 125047., Shaykhaev EG; Russian Scientific Center of Roentgen Radiology, Moscow, Russia, 117997., Kazarova MV; Russian Scientific Center of Roentgen Radiology, Moscow, Russia, 117997., Telysheva EN; Russian Scientific Center of Roentgen Radiology, Moscow, Russia, 117997., Shishkina LV; Burdenko Neurosurgical Institute, Moscow, Russia, 125047., Shibaeva IV; Burdenko Neurosurgical Institute, Moscow, Russia, 125047., Shugay SV; Burdenko Neurosurgical Institute, Moscow, Russia, 125047., Voronina EI; Novosibirsk State Medical University, Novosibirsk, Russia, 630091., Snigireva GP; Russian Scientific Center of Roentgen Radiology, Moscow, Russia, 117997.
Jazyk: ruština
Zdroj: Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko [Zh Vopr Neirokhir Im N N Burdenko] 2017; Vol. 81 (6), pp. 26-31.
DOI: 10.17116/neiro201781626-31
Abstrakt: The work explores the molecular genetic features of anaplastic astrocytomas and oligodendrogliomas in a series of 43 cases. The mutational status was studied using domestic chemicals and reagent kits. We revealed clear genetic differences between astrocytic and oligodendroglial tumors and proposed an algorithm to study diagnostic and prognostic markers.
Databáze: MEDLINE
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