PAX-5 positive anaplastic large cell lymphoma presenting by dysphagia; a case report.

Autor:	Azarpira N; Transplant Research Center, Shiraz University of Medical Science, Shiraz, Iran., Safaie A; Pathology Department, Shiraz University of Medical Science, Shiraz, Iran., Monabati A; Pathology Department, Shiraz University of Medical Science, Shiraz, Iran., Hosseinzadeh M; Pathology Department, Shiraz University of Medical Science, Shiraz, Iran., Noori S; Pathology Department, Shiraz University of Medical Science, Shiraz, Iran., Moini M; Gastroenterology Research Center, Department of Internal Medicine, Shiraz University of Medical Science, Shiraz, Iran., Rahimi A; Gastroenterology Research Center, Department of Internal Medicine, Shiraz University of Medical Science, Shiraz, Iran., Heidari T; Transplant Research Center, Shiraz University of Medical Science, Shiraz, Iran., Rahsaz M; Transplant Research Center, Shiraz University of Medical Science, Shiraz, Iran.
Jazyk:	angličtina
Zdroj:	Gastroenterology and hepatology from bed to bench [Gastroenterol Hepatol Bed Bench] 2017 Fall; Vol. 10 (4), pp. 332-336.
Abstrakt:	Anaplastic large cell lymphoma (ALCL) is a distinct pathologic entity with characteristic morphologic, im¬munophenotypic and cytogenetic features. Obstructive symptoms are rare presentation of ALCL. We report a 16-year-old boy who initially presented with dysphagia. Upper gastrointestinal endoscopy revealed severe stenosis with an infiltrative process starting from 24 cm of incisors in lower esophagus Esophageal mucosal biopsy demonstrated lymphomatous involvement that ancillary tests confirmed the diagnosis of ALCL, ALK (kinase-positive), and PAX5 positive. The patient responded to CHOP-based chemotherapy. This case illustrated an unusual presentation of primary Non Hodgkin lymphoma of esophagus. Competing Interests: The authors declare that they have no conflict of interest.
Databáze:	MEDLINE
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