Autor: |
Murauski KJR; Department of Chemistry, Department of Pharmacology, Center for Molecular Innovation and Drug Discovery, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, USA. scheidt@northwestern.edu., Jaworski AA, Scheidt KA |
Jazyk: |
angličtina |
Zdroj: |
Chemical Society reviews [Chem Soc Rev] 2018 Mar 05; Vol. 47 (5), pp. 1773-1782. |
DOI: |
10.1039/c7cs00386b |
Abstrakt: |
Catalytic, stereoselective N-heterocyclic carbene-catalyzed reactions facilitate efficient construction of many different heterocyclic compounds, such as the enantioenriched 5-membered (γ) lactones highlighted in this tutorial review. Herein, various strategies to enable formal [3+2] type annulations between electrophilic carbonyl equivalents and homoenolate nucleophiles for the synthesis of γ-lactones are summarized. |
Databáze: |
MEDLINE |
Externí odkaz: |
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