Stress-related impairments in cellular immunity.

Autor: Glaser R, Kiecolt-Glaser JK, Stout JC, Tarr KL, Speicher CE, Holliday JE
Jazyk: angličtina
Zdroj: Psychiatry research [Psychiatry Res] 1985 Nov; Vol. 16 (3), pp. 233-9.
DOI: 10.1016/0165-1781(85)90111-8
Abstrakt: The percentages of total T-lymphocytes (OKT-3+), helper T-cells (OKT-4+), and suppressor T-cells (OKT-8+) were significantly lower in blood samples obtained from 40 medical students during examinations, compared to baseline values obtained 6 weeks earlier. In addition, the response of T-lymphocytes to stimulation by phytohemagglutinin and concanavilin A was also significantly lower during examinations, compared to baseline. Self-report data documented significantly greater distress associated with examinations. The data have implications for immunosuppressive disorders and stress-related illnesses.
Databáze: MEDLINE