Squamous cell carcinoma from oral lichen planus: a case report of a lesion with 28 years of evolution.

Autor:	Silveira WDS; Department of Dentistry, University of Passo Fundo, Passo Fundo, Brazil., Bottezini EG; Department of Dentistry, University of Passo Fundo, Passo Fundo, Brazil., Linden MS; Department of Dentistry, University of Passo Fundo, Passo Fundo, Brazil., Rinaldi I; Department of Dentistry, University of Passo Fundo, Passo Fundo, Brazil., Paranhos LR; Department of Dentistry, Federal University of Sergipe, Lagarto, Brazil., de Carli JP; Department of Dentistry, University of Passo Fundo, Passo Fundo, Brazil., Trentin M; Department of Dentistry, University of Passo Fundo, Passo Fundo, Brazil., Dos Santos PL; Department of Dentistry, Sagrado Coração University, Bauru, Brazil.
Jazyk:	angličtina
Zdroj:	Journal of the Korean Association of Oral and Maxillofacial Surgeons [J Korean Assoc Oral Maxillofac Surg] 2017 Dec; Vol. 43 (Suppl 1), pp. S14-S18. Date of Electronic Publication: 2017 Dec 27.
DOI:	10.5125/jkaoms.2017.43.S1.S14
Abstrakt:	Lichen planus (LP) is a relatively common mucocutaneous disease with autoimmune etiology. Considering its malignancy potential, it is important to define the correct diagnosis, treatment, and clinical follow-up for patients with LP so that the disease is not diagnosed late, thus hindering the chances of curing the disease. This study aims to describe a clinical case of oral squamous cell carcinoma, potentially originated from LP. The patient is undergoing clinical and histopathological follow-up. A 64-year-old Caucasian male patient presented with a proliferative verrucous lesion on the tongue and sought treatment at the School of Dentistry, University of Passo Fundo (UPF), Passo Fundo, Brazil. He claimed the lesion had been present since 1988, and had been initially diagnoses as "oral lichen planus." The physical exam presented three diagnostic hypotheses: plaque-like oral LP, verrucous carcinoma, and squamous cell carcinoma. After incisional biopsy and histopathological analysis, squamous cell carcinoma was diagnosed, probably originating from oral LP. The case study shows that malignancy from oral LP is possible, which justifies periodic clinical and histopathological follow-up, as well as the elimination of risk factors for carcinoma in patients with oral LP. Competing Interests: Conflict of Interest: No potential conflict of interest relevant to this article was reported.
Databáze:	MEDLINE
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