Bilateral Non-arteritic Anterior Ischaemic Optic Neuropathy as the Presentation of Systemic Amyloidosis.

Autor: Kanaan MZ; Newcastle Eye Centre, Royal Victoria Infirmary, Newcastle Upon Tyne, United Kingdom., Lorenzi AR; Musculoskeletal Department, Freeman Hospital, Newcastle Upon Tyne, United Kingdom., Thampy N; Department of Cellular Pathology, Royal Victoria Infirmary, Newcastle Upon Tyne, United Kingdom., Pandit R; Newcastle Eye Centre, Royal Victoria Infirmary, Newcastle Upon Tyne, United Kingdom., Dayan M; Newcastle Eye Centre, Royal Victoria Infirmary, Newcastle Upon Tyne, United Kingdom.
Jazyk: angličtina
Zdroj: Neuro-ophthalmology (Aeolus Press) [Neuroophthalmology] 2017 Jun 19; Vol. 41 (6), pp. 330-334. Date of Electronic Publication: 2017 Jun 19 (Print Publication: 2017).
DOI: 10.1080/01658107.2017.1328604
Abstrakt: A 75-year-old hypertensive female with stable idiopathic intermediate uveitis presented with bilateral sequential optic neuropathy with optic disc swelling. The optic neuropathy in the first affected eye (right) was thought to be due to non-arteritic anterior ischaemic optic neuropathy (NAION). Asymptomatic left optic disc swelling was found at routine review 2 months later, and a diagnosis of giant cell arteritis (GCA) was sought. Temporal artery duplex ultrasound showed the "halo sign," but a subsequent temporal artery biopsy showed light-chain (AL) amyloidosis with no signs of giant cell arteritis. In this case, bilateral sequential ischaemic optic neuropathy mimicking non-arteritic anterior ischaemic optic neuropathy was the presenting sign of systemic amyloidosis involving the temporal arteries.
Databáze: MEDLINE
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