The impact of digital health technologies on tuberculosis treatment: a systematic review.

Autor: Ngwatu BK; Global TB Programme, World Health Organization, Geneva, Switzerland.; Both authors contributed equally., Nsengiyumva NP; Montreal Chest Institute, Respiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University Health Centre, and McGill International Tuberculosis Centre, Montreal, Canada.; Both authors contributed equally., Oxlade O; Montreal Chest Institute, Respiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University Health Centre, and McGill International Tuberculosis Centre, Montreal, Canada., Mappin-Kasirer B; Montreal Chest Institute, Respiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University Health Centre, and McGill International Tuberculosis Centre, Montreal, Canada., Nguyen NL; Global TB Programme, World Health Organization, Geneva, Switzerland., Jaramillo E; Global TB Programme, World Health Organization, Geneva, Switzerland., Falzon D; Global TB Programme, World Health Organization, Geneva, Switzerland., Schwartzman K; Montreal Chest Institute, Respiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University Health Centre, and McGill International Tuberculosis Centre, Montreal, Canada kevin.schwartzman@mcgill.ca.; For a full list of the collaborative group see the Acknowledgements.
Jazyk: angličtina
Zdroj: The European respiratory journal [Eur Respir J] 2018 Jan 11; Vol. 51 (1). Date of Electronic Publication: 2018 Jan 11 (Print Publication: 2018).
DOI: 10.1183/13993003.01596-2017
Abstrakt: Digital technologies are increasingly harnessed to support treatment of persons with tuberculosis (TB). Since in-person directly observed treatment (DOT) can be resource intensive and challenging to implement, these technologies may have the potential to improve adherence and clinical outcomes. We reviewed the effect of these technologies on TB treatment adherence and patient outcomes.We searched several bibliographical databases for studies reporting the effect of digital interventions, including short message service (SMS), video-observed therapy (VOT) and medication monitors (MMs), to support treatment for active TB. Only studies with a control group and which reported effect estimates were included.Four trials showed no statistically significant effect on treatment completion when SMS was added to standard care. Two observational studies of VOT reported comparable treatment completion rates when compared with in-person DOT. MMs increased the probability of cure (RR 2.3, 95% CI 1.6-3.4) in one observational study, and one trial reported a statistically significant reduction in missed treatment doses relative to standard care (adjusted means ratio 0.58, 95% CI 0.42-0.79).Evidence of the effect of digital technologies to improve TB care remains limited. More studies of better quality are needed to determine how such technologies can enhance programme performance.
(Copyright ©ERS 2018.)
Databáze: MEDLINE