The use of nanoparticles in wound treatment: a systematic review.

Autor:	Silva MMP; Universidade Federal do Ceará, Departamento de Enfermagem, Fortaleza, CE, Brasil., Aguiar MIF; Universidade Federal do Ceará, Departamento de Enfermagem, Fortaleza, CE, Brasil., Rodrigues AB; Universidade Federal do Ceará, Departamento de Enfermagem, Fortaleza, CE, Brasil., Miranda MDC; Universidade Federal do Ceará, Departamento de Enfermagem, Fortaleza, CE, Brasil., Araújo MÂM; Universidade Federal do Ceará, Departamento de Enfermagem, Fortaleza, CE, Brasil., Rolim ILTP; Universidade Federal do Maranhão, Departamento de Enfermagem, São Luís, MA, Brasil., Souza AMAE; Universidade Federal do Ceará, Departamento de Enfermagem, Fortaleza, CE, Brasil.
Jazyk:	Portuguese; English
Zdroj:	Revista da Escola de Enfermagem da U S P [Rev Esc Enferm USP] 2018 Jan 08; Vol. 51, pp. e03272. Date of Electronic Publication: 2018 Jan 08.
DOI:	10.1590/S1980-220X2016043503272
Abstrakt:	Objective: To analyze the effects of nanoparticle-based dressings on the wound healing process in in vitro animals and human cells based on scientific evidence. Method: A systematic review of the literature in LILACS, PubMed and Science Direct databases. The articles were selected and evaluated for the level of evidence by the application of STROBE. Results: The sample consisted of 12 articles. The application of the products occurred in surgical wounds, burns, infected wounds and gingival ulcers in laboratory animals, as well as in vitro tests, demonstrating that among other advantages, the nanoparticle-based dressings increased the healing speed, had good antibacterial capacity and were non cytotoxic agents. Conclusion: Based on the analyzed articles, it can be affirmed that dressings containing nanocomposites are quite promising and are shown as a great therapeutic option in wound healing.
Databáze:	MEDLINE
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