Elderly donor graft for liver transplantation: Never too late.

Autor:	Chela H; Department of Internal Medicine, University of Missouri, Columbia, MO 65212, United States., Yousef MH; Division of Gastroenterology and Hepatology, Missouri University, Columbia, MO 65212, United States., Albarrak AA; Division of Gastroenterology and Hepatology, Missouri University, Columbia, MO 65212, United States., Romana BS; Division of Gastroenterology and Hepatology, Missouri University, Columbia, MO 65212, United States., Hudhud DN; Department of Internal Medicine, University of Missouri, Columbia, MO 65212, United States., Tahan V; Division of Gastroenterology and Hepatology, Missouri University, Columbia, MO 65212, United States. tahanv@health.missouri.edu.
Jazyk:	angličtina
Zdroj:	World journal of transplantation [World J Transplant] 2017 Dec 24; Vol. 7 (6), pp. 324-328.
DOI:	10.5500/wjt.v7.i6.324
Abstrakt:	The definitive treatment for end stage liver disease remains a liver transplant and hence livers are needed for these patients along with cases of acute fulminant liver failure. Hence livers are a scarce and highly valuable commodity in the current time. By extending the pool of donors to include the elderly livers, it allows for increased availability of donors and reduces the mortality that is associated with the waiting list itself. There is an increasing prevalence of end stage liver disease due to conditions like chronic hepatitis B and C, non-alcoholic steatohepatitis, alcoholic liver disease. Many studies show non-inferior outcomes when elderly livers are used as a vigorous selection process is implemented. The process takes into account the characteristics of the donor, graft and recipient allowing for appropriate donor-recipient coupling. To meet the increasing demands of livers, elderly donors should be utilized for liver transplantation. The aim of this review article is to describe the aging process of the liver and the outcomes associated with use of elderly livers for transplantation. Competing Interests: Conflict-of-interest statement: All the authors have no conflicts of interests to declare. All authors of this article declare that was no conflicting interests (including but not limited to commercial, personal, political, intellectual or religious interests) that are related to the work submitted for consideration of publication.
Databáze:	MEDLINE
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