Fungal Peritonitis Caused by Rhodotorula mucilaginosa in a CAPD Patient Treated with Liposomal Amphotericin B: A Case Report and Literature Review.

Autor:	Franconieri F; Department of Internal Medicine, CHU de Caen, University of Caen - Normandie, France franconieri-f@chu-caen.fr.; Department of Nephrology, CHU de Caen, France., Bonhomme J; Department of Microbiology, CHU de Caen, France., Doriot A; Department of Internal Medicine, CHU de Caen, University of Caen - Normandie, France., Bonnamy C; Department of Visceral Surgery, Caen, France., Ficheux M; Department of Nephrology, CHU de Caen, France., Lobbedez T; Department of Nephrology, CHU de Caen, France., Béchade C; Department of Nephrology, CHU de Caen, France.
Jazyk:	angličtina
Zdroj:	Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis [Perit Dial Int] 2018 Jan-Feb; Vol. 38 (1), pp. 69-73.
DOI:	10.3747/pdi.2017.00096
Abstrakt:	Rhodotorula mucilaginosa is a ubiquitous yeast that may cause serious peritoneal dialysis (PD) infections. A 70-year-old man receiving continuous ambulatory peritoneal dialysis (CAPD) for 6 months presented with a PD infection caused by Rhodotorula mucilaginosa The patient was treated with intravenous liposomal amphotericin B. His peritoneal catheter was simultaneously removed and reinserted. To date, only 10 cases of Rhodotorula CAPD infections have been reported. Catheters, corticoids, cancer, and previous antibiotic therapy were the main risk factors for these infections. For most patients, the peritoneal catheter was removed, leading to a definitive transfer to hemodialysis. Along with flucytosine, amphotericin B is the main antifungal that is used. Both have a lower minimal inhibitory concentration (MIC), whereas fluconazole and caspofungin have the highest MICs. We highlighted the efficacy of liposomal amphotericin B associated with simultaneous withdrawal and reinsertion of a peritoneal catheter in a case of Rhodotorula peritonitis in a CAPD patient. Further studies are needed to evaluate the treatment of this condition. (Copyright © 2018 International Society for Peritoneal Dialysis.)
Databáze:	MEDLINE
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