A Technique for In Vitro Studying of the Permeability of the Spinal Cord Dura Mater.

Autor: Krasnov VV; Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics, Ministry of Health of the Russian Federation, Kurgan, Russia. v.v.krasnov@mail.ru., Stogov MV; Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics, Ministry of Health of the Russian Federation, Kurgan, Russia., Silant'eva TA; Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics, Ministry of Health of the Russian Federation, Kurgan, Russia., Kubrak NV; Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics, Ministry of Health of the Russian Federation, Kurgan, Russia., Kireeva EA; Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics, Ministry of Health of the Russian Federation, Kurgan, Russia.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2018 Jan; Vol. 164 (3), pp. 402-403. Date of Electronic Publication: 2018 Jan 08.
DOI: 10.1007/s10517-018-3999-8
Abstrakt: We propose an in vitro method for studying permeability of spinal cord dura mater for components of autological serum using an original device. Sixty native samples of the spinal cord dura mater obtained from 12 mongrel dogs were used for testing of the device. The coefficient of permeability variation (V) for blood serum substances did not exceed 5% in most cases excluding lactate (V=8.03%). Analysis of spinal cord dura mater permeability in vitro for various substances using the developed device provides reproducible results with acceptable variability (5-10%).
Databáze: MEDLINE
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