Osteogenic differentiation of mouse bone marrow stromal cells on fibroin microcarriers.

Autor: Goncharenko AV; Biological Faculty, Moscow State University, Moscow, 119992, Russia., Kotlyarova MS; Biological Faculty, Moscow State University, Moscow, 119992, Russia., Moisenovich AM; Biological Faculty, Moscow State University, Moscow, 119992, Russia., Arkhipova AY; Biological Faculty, Moscow State University, Moscow, 119992, Russia., Kulikov DA; Vladimirskii Moscow Regional Research Clinical Institute, ul. Shchepkina 61/2, Moscow, 129110, Russia., Konkov AS; Biological Faculty, Moscow State University, Moscow, 119992, Russia., Kulikov AV; Institute of Theoretical and Experimental Biophysics, Pushchino Branch, Russian Academy of Sciences, Pushchino, Moscow oblast, 142292, Russia., Mashkov AE; Vladimirskii Moscow Regional Research Clinical Institute, ul. Shchepkina 61/2, Moscow, 129110, Russia., Agapov II; Shumakov Research Institute of Transplantation and Artificial Organs, Russian Ministry of Health, Moscow, 113182, Russia., Moisenovich MM; Biological Faculty, Moscow State University, Moscow, 119992, Russia. mmoisenovich@mail.ru., Kirpichnikov MP; Biological Faculty, Moscow State University, Moscow, 119992, Russia.
Jazyk: angličtina
Zdroj: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2017 Nov; Vol. 477 (1), pp. 345-348. Date of Electronic Publication: 2018 Jan 03.
DOI: 10.1134/S1607672917060011
Abstrakt: We investigated the proliferation and osteogenic differentiation of mesenchymal stem cells cultured on fibroin microcarriers. Effective cell proliferation on the surface of the microcarriers, determined by the large surface area, and the contribution of microcarrier mineralization to the stimulation of the osteogenic differentiation of mesenchymal stem cells was revealed.
Databáze: MEDLINE