Human polyomavirus-7-associated eruption successfully treated with acitretin.

Autor: Canavan TN; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA., Baddley JW; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA., Pavlidakey P; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA., Tallaj JA; Department of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL, USA., Elewski BE; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA.
Jazyk: angličtina
Zdroj: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2018 May; Vol. 18 (5), pp. 1278-1284. Date of Electronic Publication: 2018 Jan 21.
DOI: 10.1111/ajt.14634
Abstrakt: Advances in molecular technologies have led to the discovery of several novel human polyomaviruses (HPyVs), including human polyomavirus-7 (HPyV-7). Although low levels of HPyV-7 are shed from apparently normal skin, recent reports have described clinically significant cutaneous infection in immunocompromised patients that manifests as generalized pruritic plaques. The pruritus can be severe, and treatment options have not been described. Herein we report HPyV-7 cutaneous infection in a heart transplant patient who experienced temporary improvement with intravenous cidofovir, and complete remission with acitretin. We report a case of HPyV-7 cutaneous infection demonstrating a good response to treatment.
(© 2017 The American Society of Transplantation and the American Society of Transplant Surgeons.)
Databáze: MEDLINE
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