| Autor: |
Rosa MI; Programa de Pós-Graduação em Saúde Coletiva, Universidade do Extremo Sul Catarinense (UNESC). Av. Universitária 1105, Bairro Universitário. 88806-000 Criciúma SC Brasil. mir@unesc.net., Reis MFD; Programa de Pós-Graduação em Ciências da Saúde, UNESC. Criciúma SC Brasil., Simon C; Laboratório de Epidemiologia, UNESC. Criciúma SC Brasil., Dondossola E; Laboratório de Epidemiologia, UNESC. Criciúma SC Brasil., Alexandre MC; Laboratório de Epidemiologia, UNESC. Criciúma SC Brasil., Colonetti T; Programa de Pós-Graduação em Ciências da Saúde, UNESC. Criciúma SC Brasil., Meller FO; Programa de Pós-Graduação em Saúde Coletiva, Universidade do Extremo Sul Catarinense (UNESC). Av. Universitária 1105, Bairro Universitário. 88806-000 Criciúma SC Brasil. mir@unesc.net. |
| Jazyk: |
angličtina |
| Zdroj: |
Ciencia & saude coletiva [Cien Saude Colet] 2017 Dec; Vol. 22 (12), pp. 4001-4012. |
| DOI: |
10.1590/1413-812320172212.14112016 |
| Abstrakt: |
A systematic review with meta-analysis was performed to estimate the accuracy of IgM ELISA for Leptospirosis diagnosis. A search of Medline, Lilacs, Embase, Cochrane Central Register of Controlled Trials and Grey literature (Google Scholar and British Library) was conducted. The medical subject headings (MeSHs) and the words "leptospirosis", "human leptospirosis" and "IgM ELISA" were used. Fifty-two studies were analyzed, which included 10,775 samples. The pooled sensitivity of all the studies was 86% (CI 95%, 85%-87%) and specificity was 90% (CI 95%, 89%-91%). In studies of the acute phase, the sensitivity and specificity were 84% (CI 95%, 82%-85%) and 91% (CI 95%, 90%-91%), respectively. In conclusion, IgM ELISA is sensitive for use as an initial screen for leptospiral infections. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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