The importance of direct immunofluorescence in pemphigus herpetiformis diagnosis.

Autor: Faria PCP; Dermatology Outpatient Clinic of the Department of Dermatology of the Universidade do Estado do Rio de Janeiro (UERJ) - Rio de Janeiro (RJ), Brazil., Cruz CC; Dermatology Outpatient Clinic of the Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro - Rio De Janeiro (RJ), Brazil., Abulafia LA; Dermatology Outpatient Clinic of the Department of Dermatology of the Universidade do Estado do Rio de Janeiro (UERJ) - Rio de Janeiro (RJ), Brazil.; Dermatology Outpatient Clinic of the Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro - Rio De Janeiro (RJ), Brazil., Maceira JMP; Pigmented Lesions Outpatient Clinic of the Department of Dermatology of the Universidade do Estado do Rio de Janeiro (UERJ) - Rio de Janeiro (RJ), Brazil., Cassia FF; Dermatology Outpatient Clinic of the Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro - Rio De Janeiro (RJ), Brazil., Medeiros PM; Dermatology Outpatient Clinic at Hospital do Açúcar de Alagoas do Centro Universitário Tiradentes, Maceió, Alagoas (AL), Brazil.
Jazyk: angličtina
Zdroj: Anais brasileiros de dermatologia [An Bras Dermatol] 2017; Vol. 92 (5 Suppl 1), pp. 145-147.
DOI: 10.1590/abd1806-4841.20174510
Abstrakt: Pemphigus herpetiformis is an autoimmune bullous disease, that combines clinical features of dermatitis herpetiformis and linear IgA bullous dermatosis and immunological characteristics of pemphigus, which makes this disease peculiar and this diagnosis rarely suspected in the first evaluation of the patient. The reported case is of a patient with clinically bullous disease similar to dermatitis herpetiformis, whose multiple biopsies were inconclusive, and only after direct immunofluorescence with a pemphigus pattern (intraepidermal intercellular pattern) the confirmation of the diagnosis was possible.
Databáze: MEDLINE