Metabolic investigation in patients with nephrolithiasis.

Autor: Santos FMD; Centro Universitário Faculdade Assis Gurgacz, Cascavel, PR, Brazil., Peres AK; Centro Universitário Faculdade Assis Gurgacz, Cascavel, PR, Brazil., Mandotti MR; Centro Universitário Faculdade Assis Gurgacz, Cascavel, PR, Brazil., Peres LAB; Centro Universitário Faculdade Assis Gurgacz, Cascavel, PR, Brazil.
Jazyk: English; Portuguese
Zdroj: Einstein (Sao Paulo, Brazil) [Einstein (Sao Paulo)] 2017 Oct-Dec; Vol. 15 (4), pp. 452-456. Date of Electronic Publication: 2017 Dec 18.
DOI: 10.1590/S1679-45082017AO4029
Abstrakt: Objective: To evaluate the prevalence of metabolic disorders associated with nephrolithiasis in a female population.
Methods: A retrospective study on 1,737 patients with evidence of recent formation of renal stones, being 54% females. The laboratory investigation consisted of at least two samples of blood and 24-hour urine to assess calcium, uric acid, citrate and creatinine levels, qualitative cystinuria, urinary pH following fasting and 12-hour water restriction, urine culture, serum creatinine and parathyroid hormone.
Results: The most frequent alterations were hypercalciuria (40.9%), urinary tract infection (23.2%), hypocitraturia (22.4%), low urinary volume (20.5%) and hyperuricosuria (16%).
Conclusion: The most frequent metabolic alterations in females were hypocitraturia, urinary tract infection, low urinary volume and hyperuricosuria.
Databáze: MEDLINE