Lugol Chromoscopy in the Follow-up of Head and Neck Carcinoma.

Autor: Simões CA; Department of Head and Neck Surgery, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil., Durazzo MD; Department of Head and Neck Surgery, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil., de Aquino Xavier FC; Department of Stomatology, University of São Paulo Dental School, São Paulo, Brazil., Gallottini MHC; Department of Stomatology, University of São Paulo Dental School, São Paulo, Brazil., Lourenço SV; Department of Stomatology, University of São Paulo Dental School, São Paulo, Brazil., Pinto Júnior DDS; Department of Stomatology, University of São Paulo Dental School, São Paulo, Brazil., Magacho de Andrade NM; Department of Head and Neck Surgery, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil., Miazaki AP; Department of Head and Neck Surgery, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil., Dedivitis RA; Department of Head and Neck Surgery, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil., Cernea CR; Department of Head and Neck Surgery, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
Jazyk: angličtina
Zdroj: Annals of maxillofacial surgery [Ann Maxillofac Surg] 2017 Jul-Dec; Vol. 7 (2), pp. 188-193.
DOI: 10.4103/ams.ams_95_17
Abstrakt: Introduction: Lugol is helpful in identifying early second primary tumors (SPTs) during oroscopy and pharyngoscopy, but this technique has not been assessed during follow-up visits with these patients.
Aim: The aim of this study is to describe the use of Lugol (a low-cost method) to diagnose SPTs in the oral cavity and oropharynx.
Methods: Patients treated for squamous cell carcinoma of the head and neck were randomly assigned to two groups. Group A was examined with routine oroscopy and pharyngoscopy without Lugol, and Group B was examined with routine oroscopy and pharyngoscopy without stain and with Lugol. A total of 211 patients were included during 4 years.
Results: Six oral and oropharynx carcinomas were detected in Group A. Eighteen oral and oropharynx carcinomas were detected in Group B, twelve of which were not seen without chromoscopy but were detected with Lugol.
Conclusion: Lugol increases the detection of malignant lesions compared to routine examination alone.
Competing Interests: There are no conflicts of interest.
Databáze: MEDLINE