Polyvinyl alcohol/chitosan hydrogels with enhanced antioxidant and antibacterial properties induced by lignin nanoparticles.

Autor: Yang W; University of Perugia, Civil and Environmental Engineering Department, Materials Engineering Center, UdR INSTM, Terni, Italy. Electronic address: weijun.yang2012@gmail.com., Fortunati E; University of Perugia, Civil and Environmental Engineering Department, Materials Engineering Center, UdR INSTM, Terni, Italy. Electronic address: elena.fortunati@unipg.it., Bertoglio F; Molecular Medicine Department (DMM), Center for Health Technologies (CHT), UdR INSTM, University of Pavia, Via Taramelli 3/B, 27100 Pavia, Italy; Scuola Universitaria Superiore IUSS, Palazzo del Broletto-Piazza della Vittoria, 15, 27100 Pavia, Italy; Department of Occupational Medicine, Toxicology and Environmental Risks, Istituti Clinici Scientifici Maugeri S.p.A., IRCCS, Via S. Boezio, 28, 27100, Pavia, Italy. Electronic address: federico.bertoglio01@ateneopv.it., Owczarek JS; Lodz University of Technology, Department of Molecular Physics, Lodz, Poland. Electronic address: 164040@edu.p.lodz.pl., Bruni G; Department of Chemistry, - Physical-Chemistry Section, University of Pavia, Viale Taramelli 16, 27100, Pavia, Italy. Electronic address: giovanna.bruni@unipv.it., Kozanecki M; Lodz University of Technology, Department of Molecular Physics, Lodz, Poland. Electronic address: marcin.kozanecki@p.lodz.pl., Kenny JM; University of Perugia, Civil and Environmental Engineering Department, Materials Engineering Center, UdR INSTM, Terni, Italy. Electronic address: jose.kenny@unipg.it., Torre L; University of Perugia, Civil and Environmental Engineering Department, Materials Engineering Center, UdR INSTM, Terni, Italy. Electronic address: luigi.torre@unipg.it., Visai L; Molecular Medicine Department (DMM), Center for Health Technologies (CHT), UdR INSTM, University of Pavia, Via Taramelli 3/B, 27100 Pavia, Italy; Department of Occupational Medicine, Toxicology and Environmental Risks, Istituti Clinici Scientifici Maugeri S.p.A., IRCCS, Via S. Boezio, 28, 27100, Pavia, Italy. Electronic address: livia.visai@unipv.it., Puglia D; University of Perugia, Civil and Environmental Engineering Department, Materials Engineering Center, UdR INSTM, Terni, Italy. Electronic address: debora.puglia@unipg.it.
Jazyk: angličtina
Zdroj: Carbohydrate polymers [Carbohydr Polym] 2018 Feb 01; Vol. 181, pp. 275-284. Date of Electronic Publication: 2017 Oct 24.
DOI: 10.1016/j.carbpol.2017.10.084
Abstrakt: Polyvinyl alcohol/chitosan (PVA/Ch) hydrogels containing 1 and 3wt% of lignin nanoparticles (LNPs) were prepared through a freezing-thaw procedure. Results from microstructural, thermal and mechanical characterization of LNPs based PVA/Ch demonstrated that the lowest amount of LNPs (1wt%) was beneficial, whereas the presence of agglomerates at higher LNP content limited the effect. Moreover, a different swelling behaviour was observed for hydrogels containing LNPs with respect of PVA/Ch, due to the formation of a porous honeycomb-like structure. A synergic effect of Ch and LNPs was revealed in terms of antioxidative response by DPPH (1,1-Diphenyl-2-picryl-hydrazyl) activity of migrated substances, whereas results from antimicrobial tests confirmed LNPs as effective against Gram negative bacteria (E. coli) when compared to Gram positive (S.aureus and S. epidermidis) strains. The obtained results suggested the possible use of produced PVA/Ch hydrogels incorporating LNPs in many different sectors, such as drug delivery, food packaging, wound dressing.
(Copyright © 2017 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: