Antimicrobial activity of denture adhesive associated with Equisetum giganteum- and Punica granatum-enriched fractions against Candida albicans biofilms on acrylic resin surfaces.

Autor:	Almeida NLM; a Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry , University of São Paulo , Bauru , Brazil., Saldanha LL; b Department of Botany, Institute of Biosciences , São Paulo State University (UNESP) , Botucatu , Brazil.; c Department of Biological Sciences, Faculty of Sciences , São Paulo State University (UNESP) , Bauru , Brazil., da Silva RA; a Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry , University of São Paulo , Bauru , Brazil., Pinke KH; a Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry , University of São Paulo , Bauru , Brazil., da Costa EF; a Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry , University of São Paulo , Bauru , Brazil., Porto VC; d Department of Prosthodontics and Periodontics, Bauru School of Dentistry , University of São Paulo , Bauru , Brazil., Dokkedal AL; c Department of Biological Sciences, Faculty of Sciences , São Paulo State University (UNESP) , Bauru , Brazil., Lara VS; a Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry , University of São Paulo , Bauru , Brazil.
Jazyk:	angličtina
Zdroj:	Biofouling [Biofouling] 2018 Jan; Vol. 34 (1), pp. 62-73. Date of Electronic Publication: 2017 Dec 18.
DOI:	10.1080/08927014.2017.1407408
Abstrakt:	Candida biofilms adhere to the internal surface of removable dentures, which is an etiological factor in the pathogenesis of denture stomatitis (DS). Adhesive materials are used at the base of maxillary complete dentures to improve their retention and chewing qualities. This article reports the antimicrobial activity of the enriched fractions of Equisetum giganteum and Punica granatum incorporated into a denture adhesive against C. albicans biofilm. The biofilms were induced on the surface of heat-cured acrylic resin specimens that were previously treated with a mixture of adhesive/herb extracts. The antimicrobial activity was evaluated by CFU counts, XTT reduction, and SEM and CLSM analysis. Both herb extracts amplified the anti-biofilm action of the adhesive on the acrylic resin by up to 12 h. Therefore, when these extracts were combined with COREGA®, they played a collaborative and innovative role in biofilm control and can be considered alternatives for temporary use in the treatment and/or prevention of DS.
Databáze:	MEDLINE
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