The BRICS (Bronchiectasis Radiologically Indexed CT Score): A Multicenter Study Score for Use in Idiopathic and Postinfective Bronchiectasis.
Autor: | Bedi P; MRC Center for Inflammation Research, Queen's Medical Research Institute, Edinburgh, UK. Electronic address: drpallavibedi@gmail.com., Chalmers JD; School of Medicine, University of Dundee, Dundee, UK., Goeminne PC; Department of Respiratory Disease, AZ Nikolaas, Sint-Niklaas, Belgium., Mai C; University Hospitals of Leuven, Department of Radiology, Leuven, Belgium., Saravanamuthu P; Royal Infirmary of Edinburgh, Edinburgh, UK., Velu PP; Royal Infirmary of Edinburgh, Edinburgh, UK., Cartlidge MK; MRC Center for Inflammation Research, Queen's Medical Research Institute, Edinburgh, UK., Loebinger MR; Royal Brompton, London, UK., Jacob J; Royal Brompton, London, UK., Kamal F; Royal Brompton, London, UK., Schembri N; School of Medicine, University of Dundee, Dundee, UK., Aliberti S; Department of Pathophysiology and Transplantation, University of Milan Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Adult Center Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Hill U; Cambridge Center for Lung Infection, Papworth Hospital, Cambridge, UK., Harrison M; Cambridge Center for Lung Infection, Papworth Hospital, Cambridge, UK., Johnson C; Cambridge Center for Lung Infection, Papworth Hospital, Cambridge, UK., Screaton N; Cambridge Center for Lung Infection, Papworth Hospital, Cambridge, UK., Haworth C; Cambridge Center for Lung Infection, Papworth Hospital, Cambridge, UK., Polverino E; Institut Clínic del Tòrax, Hospital Clínic de Barcelona, Barcelona, Spain., Rosales E; Institut Clínic del Tòrax, Hospital Clínic de Barcelona, Barcelona, Spain., Torres A; Institut Clínic del Tòrax, Hospital Clínic de Barcelona, Barcelona, Spain., Benegas MN; Institut Clínic del Tòrax, Hospital Clínic de Barcelona, Barcelona, Spain., Rossi AG; MRC Center for Inflammation Research, Queen's Medical Research Institute, Edinburgh, UK., Patel D; Royal Infirmary of Edinburgh, Edinburgh, UK., Hill AT; MRC Center for Inflammation Research, Queen's Medical Research Institute, Edinburgh, UK; Royal Infirmary of Edinburgh, Edinburgh, UK. |
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Jazyk: | angličtina |
Zdroj: | Chest [Chest] 2018 May; Vol. 153 (5), pp. 1177-1186. Date of Electronic Publication: 2017 Dec 13. |
DOI: | 10.1016/j.chest.2017.11.033 |
Abstrakt: | Objectives: The goal of this study was to develop a simplified radiological score that could assess clinical disease severity in bronchiectasis. Methods: The Bronchiectasis Radiologically Indexed CT Score (BRICS) was devised based on a multivariable analysis of the Bhalla score and its ability in predicting clinical parameters of severity. The score was then externally validated in six centers in 302 patients. Results: A total of 184 high-resolution CT scans were scored for the validation cohort. In a multiple logistic regression model, disease severity markers significantly associated with the Bhalla score were percent predicted FEV Conclusions: A simplified CT scoring system can be used as an adjunct to clinical parameters to predict disease severity in patients with idiopathic and postinfective bronchiectasis. (Copyright © 2017 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.) |
Databáze: | MEDLINE |
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